Land use change threatens global biodiversity and compromises ecosystem functions, including pollination and food production. Reduced taxonomic α-diversity is often reported under land use change, yet the impacts could be different at larger spatial scales (i.e.
View Article and Find Full Text PDFEpstein-Barr nuclear antigen 1 (EBNA1), a sequence-specific DNA binding protein of Epstein-Barr virus (EBV), is essential for viral genome replication and maintenance and is therefore an attractive target for the therapeutic intervention of EBV-associated cancers. Several EBNA1-specific inhibitors have demonstrated the ability to block EBNA1 function in vitro, but practical delivery strategies for these inhibitors in vivo are still lacking. Here, we report an intelligent hierarchical targeting theranostic nanosystem (denoted as mZGOCS@MnO-P5) that integrates an azide (N3) terminal dual-targeting peptide (N3-P5), a tumor microenvironment-responsive degradable MnO nanosheet, and a mesoporous ZnGaO:Cr, Sn near-infrared persistent luminescence (NIR-PL) nanosphere (mZGOCS).
View Article and Find Full Text PDFBackground: Non-invasive brain stimulation (NIBS) techniques, such as transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS), may offer an alternative treatment strategy for impulsive behaviour. By modulating brain activity, these techniques could potentially enhance impulse control and mitigate impulsivity.
Aims: To provide a comprehensive analysis of the correlation between NIBS parameters, targeted brain regions and impulsivity.
Purpose: Tissue engineering aims to recreate natural cellular environments to facilitate tissue regeneration. Gelatin methacrylate (GelMA) is widely utilized for its biocompatibility, ability to support cell adhesion and proliferation, and adjustable mechanical characteristics. This study developed a GelMA and graphene bioink platform at concentrations of 1, 1.
View Article and Find Full Text PDFGallium sulfide (GaS) stands out as a versatile nonlinear optical material for green-blue optoelectronic and photocatalytic nano-devices. In addition, the in-plane breaking strain and mechanical strength of layered GaS make it a promising candidate for next-generation flexible nanodevices. The fast and reliable assessment of the number of layers, without sample loss, is key for these applications.
View Article and Find Full Text PDFThis in vitro study aimed to analyze the surface roughness (Ra) and color stability (ΔEab, ΔE00) following simulated mechanical brushing and to evaluate the microtensile (μTBS) of self-adhering resin flowable (SARF) to dentin. The selected materials were Constic, Yflow AS, and Tetric N flow (TNF/control). Thirty composite resin cylinders were fabricated for surface property evaluation.
View Article and Find Full Text PDFHerein, we report the efficient photocatalytic degradation of the diclofenac drug using the ZnPrAlO photocatalyst [x, y] = (0.00, 0.00), (0.
View Article and Find Full Text PDFMechanoluminescence (ML) phosphors have found various promising utilizations such as in non-destructive stress sensing, anti-counterfeiting, and bio stress imaging. However, the reported NIR MLs have predominantly been limited to bulky particle size and weak ML intensity, hindering the further practical applications. For this regard, a nano-sized ZnGaO: Cr NIR ML phosphor is synthesized by hydrothermal method.
View Article and Find Full Text PDFWe report on a polarization-resolved study of mid-infrared emission properties of Er-doped orthorhombic yttrium aluminum perovskite YAlO single crystal. For the I→ I Er transition, the stimulated emission cross section is 0.20 × 10cm at 2919 nm for light polarization E ‖ c.
View Article and Find Full Text PDFBackground: Children diagnosed with cerebral palsy (CP) often experience various limitations, particularly in gross motor function and activities of daily living. Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation technique that has been used to improve movement, gross motor function, and activities of daily living.
Objective: This study aims to evaluate the potential additional effects of physiotherapy combined with tDCS in children with CP in comparison with physiotherapy only.
A Tm:LiYF laser operating on the H→ H transition is embedded in a high-power diode-pumped Nd:ASL laser for intracavity upconversion pumping at 1.05 µm. This leads to a record-high output power at 2.
View Article and Find Full Text PDFWe present a study on the green synthesis of undoped and Er-doped ZnO compounds using gum (MI). A set of tests were conducted to assess the structure of the material. The tests included X-ray diffraction, Raman, and Fourier-transform infrared spectroscopy.
View Article and Find Full Text PDFPollination is a key ecosystem service of critical importance for food production. However, globally, several regions are already experiencing pollinator shortage as pollinators are declining. Here, we investigate the origin, pollinator dependence and economic value of 199 food crops cultivated in Brazil to understand to which extent (1) Brazilian agriculture is vulnerable to pollinator shortage, and (2) Brazilian society has already achieved a comprehensive perspective about crop dependence.
View Article and Find Full Text PDFThe green-emitting SrAlO:Eu,Dy phosphor is the most widely used and well-studied persistent luminescent phosphor available today. Recent efforts to boost its performance in terms of luminescence intensity and duration are challenged by complex loss mechanisms, including the optically stimulated release of previously trapped charges by excitation light. Here, we present minimally scattering SrAlO:Eu,Dy single crystals, which, as opposed to powder phosphors, allow to profit from a so-called volume effect, resulting in a significantly increased emission intensity.
View Article and Find Full Text PDFCarbon-based nanomaterials (CBNs) are a category of nanomaterials with various systems based on combinations of sp2 and sp3 hybridized carbon bonds, morphologies, and functional groups. CBNs can exhibit distinguished properties such as high mechanical strength, chemical stability, high electrical conductivity, and biocompatibility. These desirable physicochemical properties have triggered their uses in many fields, including biomedical applications.
View Article and Find Full Text PDFBiomedical photothermal therapy with optical nanoparticles is based on the conversion of optical energy into heat through three steps: optical absorption, thermal conversion of the absorbed energy and heat transfer to the surrounding medium. The light-to-heat conversion efficiency (LHCE) has become one of the main metrics to quantitatively characterize the last two steps and evaluate the merit of nanoparticules for photothermal therapy. The estimation of the LHCE is mostly performed by monitoring the temperature evolution of a solution under laser irradiation.
View Article and Find Full Text PDFObjective: to translate, culturally adapt and validate the Multidimensional Individual and Interpersonal Resilience Measure to Brazilian Portuguese.
Method: after initial translation, the pre-final version underwent rigorous cultural adaptation procedures. As a result, the final adapted version was submitted to a validity study.
Persistent luminescence nanoparticles (PLNPs) are innovative materials able to emit light for a long time after the end of their excitation. Thanks to this property, their detection can be separated in time from the excitation, making it possible to obtain images with a high signal-to-noise ratio. This optical property can be of particular interest for the development of in vitro biosensors.
View Article and Find Full Text PDFNear-infrared (NIR) persistent luminescence (PersL) materials have demonstrated promising developments for applications in many advanced fields due to their unique optical properties. Both high-temperature solid-state (SS) or hydrothermal (HT) methods can successfully be used to prepare PersL materials. In this work, ZnGaSnO:0.
View Article and Find Full Text PDFGlobally, human activities impose threats to nature and the provision of ecosystem services, such as pollination. In this context, ecological restoration provides opportunities to create managed landscapes that maximize biodiversity conservation and sustainable agriculture, e.g.
View Article and Find Full Text PDFWe report on the first laser operation of a disordered Tm:CaGdAlO crystal on the H → H transition. Under direct pumping at 0.79 µm, it generates 264 mW at 2.
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