Background: Studies of trauma systems have identified traumatic brain injury as a frequent cause of death or disability. Due to the heterogeneity of patient presentations, practice variations, and potential for secondary brain injury, the importance of early neurosurgical procedures upon survival remains controversial. Traditional observational outcome studies have been biased because injury severity and clinical prognosis are associated with use of such interventions.
View Article and Find Full Text PDFBackground: Our goal was to use a hospital population-based data set that was a sample of all injured patients admitted to a hospital in the United States to develop universal measures of outcome and processes of care.
Methods: Patients with a primary discharge diagnosis of injury (ICD-9 800 to 959) in the HCUP/Nationwide Inpatient Sample for the years 1995 to 2000 were used to estimate the annual number of hospitalized injured patients. Using census data, we calculated age- and sex- adjusted average annual incidence rates for four census regions in the United States: Northeast, Midwest, South and West.
Background: Autologous transplantation is increasingly used to treat epithelial ovarian cancer. However, it is not clear which patients may benefit.
Objective: To determine overall and progression-free survival and factors associated with favorable outcome after autotransplantation for ovarian cancer.
Allogeneic bone marrow transplantation (BMT) is the only curative therapy for chronic myelogenous leukemia (CML), though several studies indicate that prolonged survival can result from interferon-alpha (IFN-alpha) treatment. IFN-alpha is now often used as initial therapy for CML, before donor availability is known. Because identifying potential donors can take several weeks to months, it is important to know whether IFN-alpha adversely affects outcome of a subsequent BMT.
View Article and Find Full Text PDFObjective: Evaluate the influence of implementing the Oregon statewide trauma system on admission distribution and risk of death.
Design: Retrospective pre- and posttrauma system analyses of hospital discharge data regarding injured patients with one or more of the following injuries: head, chest, spleen/liver, pelvic fracture, and femur/tibia fracture.
Materials And Methods: Risk-adjusted odds ratio of admission to Level I or II (tertiary care) trauma centers, and odds ratio of death were determined using hospital discharge abstract data on 27,633 patients.
Study Objective: To document the validity of a Hospital Discharge Index (HDI) as a data base on injured patients.
Design: Patient information in trauma registries was compared with information in HDI.
Population: Injured patients admitted to trauma centers.
Objective: To determine if risk of death for hospitalized injured patients changes when an urban trauma system is implemented.
Design: An analysis of the risk of death in hospitalized injured patients in 1984 and 1985 (pretrauma system), 1986 and 1987 (early trauma system), and 1990 and 1991 (established trauma system) using hospital discharge abstract data.
Setting: A total of 18 acute care hospitals in the four-county area encompassing Portland, Ore.
Objective: To determine whether age over 40 years is associated with adverse outcome after allogeneic bone marrow transplantation for leukemia.
Design: A retrospective analysis of outcome after bone marrow transplants for leukemia reported to the International Bone Marrow Transplant Registry (IBMTR) among recipients 30 through 39 years, 40 through 44 years, 45 through 49 years, and 50 years of age and older.
Setting: Transplantations performed in 138 institutions worldwide and reported to the IBMTR.