The value of P300 event related potentials in the assessment of cognitive function in subclinical hypothyroidism.

Background: Mild hypothyroidism (thyroid stimulating hormone [TSH] less than 10 mIU/L) induces reversible cognitive dysfunction, which can be evaluated by event related potentials (ERP). So far, only little is known about the impact of subclinical hypothyroidism on ERP as electrophysiological markers of cognitive activity. The aim of this study was to follow-up P300 latencies and amplitudes in patients with subclinical hypothyroidism and to evaluate the influence of thyroxine treatment which led to the normalization of TSH level in serum.

The role of P300 event-related potentials in the cognitive recovery after the stroke.

The aim of this study was to elucidate the effects of an ischemic stroke on the amplitude and latency of the P300 wave and evaluate their changes over a prospective 1-year follow-up period. We recorded the P300 wave using an auditory oddball paradigm in 60 consecutive brain infarct patients at baseline (i.e.

Heterophoria and fusional convergence and divergence in preschool children.

Aim: To determine the prevalence of heterophoria, fusional convergence and divergence values and the degree of relationship between heterophoria and fusional vergence in preschool children.

Methods: For assessment of far and near heterophoria in 152 children aged 6-7, cover and prism cover tests were used. Far and near fusional vergences were measured by step vergence testing using prism bars.

Effects of St John's wort (Hypericum perforatum L.) extracts on epileptogenesis.

The purpose of this study was to investigate the effects of treatment with water, n-butanol and ether extracts of Hypercom perforatum L. on epileptogenesis in rabbits. Animals from the control group received solvent-ethanol, and the kindling model of epilepsy was used.

Risk of the recurrent headache and migraine appearance within the family.

Aim: The aim of this research was to determine the risk for family appearance of the recurrent headache (non-migraine and migraine).

Methods: The research was conducted in Vojvodina, the Northern Province of Serbia. The population of Vojvodina is around 2 million people belonging to more than 20 different ethnic groups.

[Effects of calcium antagonists on brain ischemia].

Introduction: Stroke is the second leading cause of death in the world and the leading cause of serious, long-term disability in adults; about half of those who survive become dependent on others in performing personal activities of daily living. Ischemia disturbs calcium cellular homeostasis, whereas calcium channel blockers re-establish it. This study was aimed at assessing benefits of calcium channel blockers on the outcome of rehabilitation of the patients afflicted by ischemic stroke.

[Relaxant activity of aqueous and ethanol extracts of parsley (Petroselinum crispum (Mill) Nym. ex A. W Hill, Apiaceae) on isolated ileum of rat].

Introduction: Parsley (Petroselinum crispum) is used in the traditional herbal medicine to treat intestinal disorders. The aim of this study was to examine the effect of aqueous and ethanol extracts of parsley on spontaneous and acetylcholine induced contractions on isolated rat ileum.

Material And Methods: Wistar albino rats (250-300 g) were used in this study.

Comparison of the hypotensive and bradycardic activity of ginkgo, garlic, and onion extracts.

The acute effect of ethanol extracts ginkgo (Ginkgo biloba L.), garlic (Allium sativum L.), and onion (Allium cepa L.

Inhibitory effect of aqueous and ethanolic garlic (Allium sativum L., Lilliaceae) extracts on the rat atria.

The acute negative inotropic and chronotrophic effects of aqueous and alcoholic garlic extracts (Allium sativum L.) on spontaneous and adrenalin-stimulated contractions of the Wistar rat atria were investigated. The addition of garlic extracts to isolated rat atria evoked negative inotropic and chronotropic effects.

Inhibitory effect of Ginkgo biloba extract on the tonus of the small intestine and the colon of rabbits.

Ginkgo biloba is widely used in folk medicine. Patients very often use the plant preparation with no concern for purity. They also tend to increase the dosage by themselves and this may result in certain insufficiently researched acute effects.

Effect of 12-monoketocholic acid on modulation of analgesic action of morphine and tramadol.

This work is concerned with the potential promotive action of 12-monoketocholic acid (12-MKC) on the analgesic effect of morphine and tramadol. The investigation was carried out on laboratory Wistar rats divided into five test groups, each treated with either morphine (2 mg/kg), tramadol (9.6 mg/kg), 12-MKC (2 mg/kg), morphine + 12-MKC, or tramadol + 12-MKC, the control group receiving physiological solution (2 mg/kg).

Effects of mistletoe (Viscum album L., Loranthaceae) extracts on arterial blood pressure in rats treated with atropine sulfate and hexocycline.

Acute effects of different extracts of mistletoe stem (Viscum album) were investigated on values of arterial blood pressure in Wistar rats. Arterial blood pressure was registered by direct method in the left carotid artery and the investigated extracts (total ethanol, ether and ethyl acetate) of mistletoe stem were administered into the right jugular vein. The total ethanol extract exhibited the best effect even on the lowest applied concentration (3.

The effect of Ginkgo biloba (EGb 761) on epileptic activity in rabbits.

Different animal models are used to evaluate the process of epileptogenesis. In this investigation the kindling model of epilepsy was used. The epileptic focus was induced in Chinchilla rabbits by stimulation of the hippocampus with electric stimuli.

[Event-related potentials following exercise bouts of different intensity].

Introduction: A number of articles on physical activity analyze the effects of acute bouts of physical exercise on the whole body. These experiments mainly include questionnaires and measurements of reaction time. The use of event-related potentials in laboratories for functional diagnostics is only of recent date.

[Effects of ginkgo biloba extract on an experimental model of epilepsy].

Introduction: The active ingredients of ginkgo biloba extracts were determined by biochemical analyses in the last ten years and they are widely used in classical medicine. The active substances of ginkgo biloba extract, mostly affect muscarinic receptors and adrenergic receptors to a lesser degree. Recently, potential effects of ginkgo biloba on NMDA receptors and on epileptogenic seizures have been considered.

[Olfactory perception in women with physiologically altered hormonal status (during pregnancy and menopause].

Introduction: Olfaction is considered to be the ability to: perceive, conduct and recognize scents and odors. With its numerous connections to the limbic system and reticular formation, the olfactory system affects regulation of numerous vegetative functions, visceral functions and sexual behavior. Since estrogen and progesterone protect the olfactory function, changes in their levels in particular physiological states in women (in pregnancy and posmenopause) exert an influence on the ability to feel and recognize smells.

[The effect of age on the sense of smell in health individuals].

Introduction: A need for research of the olfactory function exists in everyday clinical work. The aim of this study was to determine standards for perception and identification thresholds regarding olfactory substances in healthy subjects in regard to their age.

Material And Methods: The research included 120 healthy examinees (60 women and 60 men) classified according to age into three age groups (20-30, 31-40, 41-50 years of age).