How Does Indonesian Chronic Disease Patient Adhere to Their Treatment? A Cross-Sectional Analysis of 11,408 Subjects.

Background: Chronic disease has become an increasing burden in Indonesia, increasing the importance of treatment adherence to control the disease prognosis. Therefore, we aim to determine the prevalence and characteristics of nonadherence in Indonesian chronic disease population.

Methods: We identified 11,408 adult subjects with chronic diseases from the fifth Indonesian Family Life Survey.

Surgical Excision and Radiotherapy for Giant Keloids in Auricula: A Case Report.

Keloids are characterized by excessive growth of fibrous tissue resulting from abnormal wound-healing processes. They may lead to functional impairments, aesthetic deformities, pruritus, and a decreased quality of life. Various therapies, including intralesional corticosteroid injections, cryotherapy, laser therapy, surgical excision, and radiotherapy, have been used to manage keloids, but the recurrence rates remain high.

The Role of Vitamins A and E Level in Chronic Suppurative Otitis Media with and without Cholesteatoma.

Aim: High expression of lytic enzymes and cytokines is related to cell proliferation in Otitis Media Chronic Suppurative (CSOM) with cholesteatoma. In addition, the process of inflammation healing and maintenance of homeostatic conditions requires Reactive Oxygen Species (ROS), which can cause significant damage to cells. To address this issue, secondary antioxidants such as Vitamins A and E are used to inhibit and neutralize the occurrence of oxidation reactions.

Traditional medicine users in a treated chronic disease population: a cross-sectional study in Indonesia.

Background: Traditional medicine (TM) is commonly used as a treatment in Indonesia. This raises the need for an analysis of its potential development and irrational use. Therefore, we analyze the proportion of TM users among chronic disease patients and its associated characteristics to optimize the use of TM in Indonesia.

Determination of the Difference Between Men and Women Anthropometry Auricles Using Photogrammetric Method in Sundanese Ethnic Group.

Abstract: Auricle is one of the features that determine the face appearance. Furthermore, its shape and size are influenced by age, gender, and ethnicity. Knowledge of the normal dimensional shape, ear growth patterns, and deformity is important in diagnosing various congeital disorders.

Calcitriol potentially alters HeLa cell viability via inhibition of autophagy.

Objective: This study was conducted to evaluate the effect of Calcitriol on cellular death in HeLa cells via autophagy and turn over due to mitochondria homeostasis.

Methods: HeLa cell lines were grown in 24-well plates and treated with Calcitriol at varying doses (0.013 μM-0.

Polyethyleneimine (PEI) as a Polymer-Based Co-Delivery System for Breast Cancer Therapy.

Cancer has become one of the leading causes of morbidity and mortality worldwide. This disease is classified broadly by tissue, organ, and system; different cancer types and subtypes require different treatments. Drug bioavailability, selectivity, and high dosage, as well as extended treatment, are significantly associated with the development of resistance - a complex problem in cancer therapy.

The application of honey in wound care of raw surface at spontaneous rupture submandibular abscess that extends to submental and right neck: A case report.

Introduction: Honey has been reported to accelerate wound healing. The use of honey in wound care mostly uses medicated (Manuka) honey. There are still few who report using Nusantara honey, local honey from Indonesia, as a wound dressing.

Vitamin D Inhibits Lipopolysaccharide (LPS)-Induced Inflammation in A549 Cells by Downregulating Inflammatory Cytokines.

BACKGROUND Studies have shown that lung inflammation affects lung function, with life-threatening results. Vitamin D may play an important role in inhibiting inflammatory cytokines. Vitamin D deficiency is related to several lung problems, including respiratory distress syndrome, alveolar inflammation, epithelial damage, and hypoxia.

Lack of Awareness of the Impact of Improperly Disposed Of Medications and Associated Factors: A Cross-Sectional Survey in Indonesian Households.

Disposal of unused medications through environmentally unsafe routes is common in Indonesia. The lack of awareness of the impact of improperly disposed of medications is a significant contributing factor. The objectives of this study were to identify factors associated with lack of awareness of the impact of improperly disposed of unused medications and to assess the associations of awareness with medication disposal practices among the general population in Indonesia.

Improper disposal practice of unused and expired pharmaceutical products in Indonesian households.

Background: Improperly disposed medicines could adversely affect the environment and increase the risk of drug misuse or accidental poisoning.

Objective: To evaluate the disposal practices of unused and expired medicines among the general population in Bandung, Indonesia.

Method: This was a descriptive cross-sectional survey conducted among 497 respondents in Bandung, Indonesia.

Updates on the Status of Vitamin D as a Risk Factor for Respiratory Distress Syndrome.

To update the guidelines regarding vitamin D status in respiratory distress syndrome, we reviewed recent human and animal studies on the benefits of vitamin D in respiratory distress. We searched PubMed and ProQuest for studies on the use of vitamin D from 2009 to 2017. The common parameters in these studies included the use of lung tissue, phospholipids, blood, and plasma to assess the effects of vitamin D on respiratory syndrome.