Publications by authors named "Vesa Kirjavainen"
Article Synopsis
- SARS-CoV-2, the virus responsible for COVID-19, was first detected in Finland in January 2020 and has since caused fewer infections compared to other European countries.
- A study analyzed the virus's lineage origins and dynamics in Finland, revealing 42 independent introductions in spring 2020, primarily from Italy, Austria, and Spain.
- Findings indicated that one introduction from Spain caused about a third of the cases in Finland during that period, highlighting the impact of travel on virus spread and the importance of early public health measures.
Background: Understanding the false negative rates of SARS-CoV-2 RT-PCR testing is pivotal for the management of the COVID-19 pandemic and it has implications for patient management. Our aim was to determine the real-life clinical sensitivity of SARS-CoV-2 RT-PCR.
Methods: This population-based retrospective study was conducted in March-April 2020 in the Helsinki Capital Region, Finland.
Background And Aims: We assessed the possibility to rule out negative urine cultures by counting with UriSed 3 PRO (77 Elektronika, Hungary) at Helsinki and Uusimaa Hospital District.
Materials And Methods: Bacteria counting of the UriSed 3 PRO automated microscope was verified with reference phase contrast microscopy against growth in culture. After acceptance into routine, results of bacteria and leukocyte counting from 56 426 specimens with eight UriSed 3 PRO instruments were compared against results from parallel samples cultured on chromogenic agar.
Background And Aims: Ten UriSed 3 PRO automated microscopes (77 Elektronika, Hungary) were verified for nine HUSLAB laboratories with 160 000 annual urine samples.
Materials And Methods: Particle counting of the primary UriSed 3 PRO instrument (77 Elektronika, Hungary) was verified against reference visual microscopy with 463 urine specimens, and against urine culture on chromogenic agar plates with parallel 396 specimens. Nine secondary instruments were compared pairwise with the primary instrument.
The value of surveillance cultures in predicting systemic infections and in guiding antimicrobial treatment is controversial. We investigated 57 pediatric allo-SCTs between 2007 and 2009. ALL (34), AML (5), and severe aplastic anemia (4) were the largest patient groups.
View Article and Find Full Text PDFAil is a 17-kDa chromosomally encoded outer membrane protein that mediates serum resistance (complement resistance) in the pathogenic Yersiniae (Yersinia pestis, Y. enterocolitica, and Y. pseudotuberculosis).
View Article and Find Full Text PDFMany pathogens are equipped with factors providing resistance against the bactericidal action of complement. Yersinia enterocolitica, a Gram-negative enteric pathogen with invasive properties, efficiently resists the deleterious action of human complement. The major Y.
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