Publications by authors named "Veronique Jestin-Le Tallec"
The discovery of a cancer for which there is no immediate curative option is a frequent occurrence in the elderly. This article describes two well-identified pathways coordinated by advanced practice nurses at our facility: the oncogeriatric pathway and the early palliative pathway, as well as the link between these pathways.
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- Trifluridine/tipiracil (FTD/TPI) combined with oxaliplatin is being studied for its effectiveness and safety in patients with advanced gastric cancers who can't handle standard chemotherapy.
- The research aims to compare this combination treatment against the standard FOLFOX regimen, focusing on improving progression-free survival (PFS).
- The ongoing PRODIGE73-UCGI40-LOGICAN trial includes 118 patients and will provide valuable insights into treatment options for HER2 negative gastric cancer in a first-line setting.
The main aim of this study was to evaluate the prognostic value of radiomic approach in pre-therapeutic F-fluorodeoxyglucose positron-emission tomography (FDG-PET/CT) in a large cohort of patients with gastro-esophageal junction cancer (GEJC). This was a retrospective monocenter study including 97 consecutive patients with GEJC who underwent a pre-therapeutic FDG-PET and were followed up for 3 years. Standard first-order radiomic PET indices including SUV, SUV, SUV, MTV and TLG and 32 textural features (TFs) were calculated using LIFEx software on PET imaging.
View Article and Find Full Text PDFCan we predict chemo-induced hematotoxicity in elderly patients treated with pegylated liposomal doxorubicin? Results of a population-based model derived from the DOGMES phase II trial of the GINECO.
J Geriatr Oncol
January 2013
Introduction: Use of anthracyclines is often limited in older patients due to cardiac and hematologic toxicities. Thanks to its reduced toxicity profile, Pegylated Liposomal Doxorubicin (PLD) allows an extended use of doxorubicin to this population. We aimed at modeling PLD-induced hematotoxicity in patients with metastatic breast cancer ≥70 years old and at finding predictive factors of neutrophil nadir value.
View Article and Find Full Text PDFObjectives: Esophageal cancer outcome greatly depends on the pathological stage. Our objectives were to assess prognosis on the basis of the initial fluorodeoxyglucose (FDG)-PET scan, focusing on the correlation between overall survival and FDG uptake in the primary, as well as the presence of FDG-positive lymph nodes or distant metastases.
Methods: Fifty-two esophageal cancer patients undergoing FDG-PET as part of initial routine staging procedure before treatment were included.