Publications by authors named "Veronique Derouin"

The genus Enterobacter includes species responsible for nosocomial outbreaks in fragile patients, especially in neonatal intensive care units (NICUs). Determining the primary source of infection is critical to outbreak management and patient outcomes. In this investigation, we report the management and control measures implemented during an Enterobacter outbreak of bloodstream infections in premature babies.

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Background: The issue of contact precautions as contributory factors for reducing Pseudomonas aeruginosa (Pa) infections in intensive care units (ICUs) remains questioned. We evaluated the impact of the addition of contact precautions to standard precautions for Pa-positive patients on incidence of ICU-acquired Pa infections.

Methods: In this multicenter, cluster-randomized crossover trial, 10 French ICUs were randomly assigned (1:1) to sequence 0-1 (6-month control period [CP]/3-month washout period/6-month intervention period [IP]) or sequence 1-0 (6-month IP/3-month washout period/6-month CP).

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Although Pseudomonas aeruginosa has a non-clonal epidemic population structure, recent studies have provided evidence of the existence of epidemic high-risk clones. The aim of this study was to assess the molecular epidemiology of P. aeruginosa isolates responsible for infections in French ICUs, regardless of resistance patterns.

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Article Synopsis
  • The study investigates the causes of coagulase-negative staphylococcal bloodstream infections (CR-BSIs) in preterm neonates, focusing on the role of central venous catheters (CVCs) and exploring other potential transmission methods.
  • Researchers developed a quantitative polymerase chain reaction (qPCR) assay to detect Staphylococcus DNA in CVCs and found that among 34 CVCs that yielded negative cultures, 23.5% tested positive for Staphylococcus DNA.
  • The findings suggest that the connection between CVCs and CR-BSIs is complex, indicating that in some cases, the CVC may not be the sole culprit for infections
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