Publications by authors named "Veronika Urdova"
Real-world outcomes of mepolizumab treatment in severe eosinophilic asthma patients - retrospective cohort study in Slovakia.
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub
September 2023
Article Synopsis
- Mepolizumab, a monoclonal antibody targeting IL-5, is effective in improving asthma control and lung function in severe eosinophilic asthma patients based on real-world data from Slovakia.
- A retrospective study analyzed medical records of 17 adult asthma patients who started mepolizumab treatment between 2017 and 2019, focusing on changes in health over a year.
- Results showed significant reductions in severe exacerbations, blood eosinophil counts, and oral corticosteroid use, along with improved lung function and a decrease in nasal polyps, supporting mepolizumab's efficacy in routine clinical practice.
This study aimed to establish physiological TREC/KREC values in a healthy population of different ages to create cut-offs and analyze pediatric patients with various inborn errors of immunity. Dry blood spots and DNA samples purified from whole blood were used for TREC/KREC quantification using real-time PCR. Observed difference (p < 0.
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