Publications by authors named "Veronika Grassmann"
Article Synopsis
- The development of effective vaccines against viruses like HIV, influenza, and hepatitis C faces challenges due to the need for broadly neutralizing antibodies.
- A new technology involving mammalian cell surface display and monoclonal antibody panning enables the selection of different envelope (Env) variants from libraries, linking genotype and phenotype effectively.
- This approach successfully enriched high affinity Env variants using fluorescence-activated cell sorting, demonstrating its potential in identifying optimized vaccine candidates and possibly aiding the creation of vaccines for various pathogens.
Background: Age-related macular degeneration (AMD) is a common condition of vision loss with disease development strongly influenced by environmental and genetic factors. Recently, 34 loci were associated with AMD at genome-wide significance. So far, little is known about a genetic overlap between AMD and other complex diseases or disease-relevant traits.
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