Publications by authors named "Veronica V Burunova"
Intra-Arterial Stem Cell Transplantation in Experimental Stroke in Rats: Real-Time MR Visualization of Transplanted Cells Starting With Their First Pass Through the Brain With Regard to the Therapeutic Action.
Daria D Namestnikova Ilya L Gubskiy Veronica A Revkova Kirill K Sukhinich Pavel A Melnikov Veronica V Burunova
Front Neurosci
March 2021
Article Synopsis
- - Cell therapy, particularly using directly reprogrammed neural precursor cells (drNPC), shows promise for reducing brain damage and improving recovery after a stroke, as tested in a rat model.
- - The study involved infusing drNPC into the bloodstream of rats 24 hours post-stroke, allowing tracking of these cells via MRI; results indicated that drNPC were present near and within the infarct zone more quickly than the control group of placenta-derived mesenchymal stem cells (pMSC).
- - Both drNPC and pMSC improved neurological function and reduced stroke effects, but they acted differently in terms of infarct volume and animal survival, hinting at unique therapeutic mechanisms at play, particularly for drNPC.