A Global Assessment of Circulating Prolysyl Oxidase in Nonischemic Patients With Garden-variety Heart Failure With Preserved Ejection Fraction.

Introduction And Objectives: Lysyl oxidase is overexpressed in the myocardium of patients with hypertensive cardiomyopathy. We aimed to explore whether patients with hypertensive-metabolic heart failure with preserved ejection fraction (HM-HFpEF) also have increased concentrations of circulating prolysyl oxidase (cpLOX) and its possible consequences.

Methods: We quantified cpLOX concentrations in 85 nonischemic patients with stage C, HM-HFpEF, and compared them with those of 51 healthy controls.

[Controversy over one use only medical devices].

At the present time, concern has arisen as to whether or not medical devices designed for one use only should be reutilized after the appearances of outbreaks of Hepatitis C infections in Spain as well as in other countries. 80% of Spanish hospitals, both public and private, reprocess these one use only devices; there is no regulation at this time which guarantees this practice. The increase in endoscopic surgeries has led to an increase in health care costs, plus an increase in the residues which derive from their use.