Publications by authors named "Veronica Minei"
J Appl Lab Med
September 2024
Article Synopsis
- Heparin-induced thrombocytopenia (HIT) is a serious condition caused by antibodies that activate platelets and accurate diagnosis is crucial but difficult; this study aimed to assess a new diagnostic laboratory algorithm for suspected HIT using specific immunoassays.
- The study analyzed 163 patients, utilizing a two-step approach with Chemiluminescence (CliA) followed by ELISA testing to rule out or confirm HIT; the algorithm successfully excluded HIT in 88% of cases and made predictions about platelet aggregation in a subset of patients.
- The findings showed a HIT prevalence of 3.1%, consistent with existing literature, and indicated that the combined approach could quickly rule out HIT in a majority of patients, although individual
