J Orthop Trauma
February 2011
Objective: To develop an initiative using standardized discharge orders to improve the posthip fracture care of patients aged 50 years or older.
Design: Prospective nonrandomized study.
Setting: Hospital orthopaedic service.
Background: Gastrointestinal (GI) symptoms and high dosing frequency have been cited as reasons for inadequate adherence to daily or weekly oral bisphosphonate therapy. Inadequate adherence may lead to poor therapeutic outcomes.
Objective: The PRIOR study evaluated adherence to and GI tolerability of monthly therapy with oral and quarterly intravenous ibandronate in postmenopausal women with osteoporosis or osteopenia.
Objective: To examine the association between back pain and health related quality of life (HRQOL) in postmenopausal women with osteoporosis.
Methods: The Fracture Prevention Trial was a prospective double blinded, placebo controlled study designed to compare the proportion of women receiving teriparatide who experienced a new fracture to the proportion of women receiving placebo who experienced a new fracture. Subjects were ambulatory postmenopausal women with osteoporosis and prior vertebral fracture.