Projected clinical outcomes of glaucoma screening in African American individuals.

Objectives: To project the clinical impact of routine glaucoma screening on visual outcomes in middle-aged African American individuals and help guide glaucoma screening policy.

Methods: Using data from the Eye Diseases Prevalence Research Group and Baltimore Eye Study, we developed a microsimulation model to project visual outcomes in African American individuals screened for glaucoma under a national screening policy using frequency-doubling technology. We projected the impact of universal screening on glaucoma-related visual impairment (acuity worse than 20/40 but better than 20/200 in the better-seeing eye) and blindness (acuity 20/200 or worse in the better-seeing eye).

Exposure of Tg.AC transgenic mice to benzene suppresses hematopoietic progenitor cells and alters gene expression in critical signaling pathways.

The effects of acute benzene (BZ) exposure on hematopoietic progenitor cells (HPCs) derived from bone marrow cells were studied using homozygous male v-Ha-ras Tg.AC mice at 8-10 weeks of age. The mice were given 0.