[Comprehensive treatment of patient with class III malocclusion complicated by partial teeth absence].

The article presents the results of planning and comprehensive treatment of a patient with class III malocclusion complicated by partial teeth absence. Split osteotomy of the mandible improved the relationship of dental arches facilitating complete oral restorative rehabilitation with adequate functional load distribution and esthetic harmony.

[The surgical procedure in trauma to the cervical spine].

The authors experience based upon the results of operative treatment of 148 patients with injuries of the cervical spine and dysfunctions of the upper extremities was used in order in substantiate the volume of diagnostic measures, indications to different methods of operative treatment. The latter is considered to be expedient in all periods of the traumatic disease of the spinal cord with retained radicular-medullary compression.

[The therapeutic aspects of the treatment and rehabilitation of minor casualties in neurosurgery].

The article is based on the data obtained in the result of examination of 53 wounded with closed cranial injuries (slight and middle gravity cases), and 34 wounded with spine injuries, but without spinal marrow traumas. The activity of fibroblasts of spinal marrow was studied, as well as the functional activity of peripheral blood monocytes during a ten-day posttraumatic period. It was found out that patients had refractory anemia with a diminishing number of erythroid cells, and also initial infectious complications, such as pneumonia or wound suppuration.

[The organization of the treatment of minor casualties in neurosurgery].

The selection of neurosurgical minor wounded during casualty staging has a number of specific features. First of all it is caused by objective difficulties in the diagnosis of wounds and traumas of nervous system. Patients who have even minimal traumas of soft tissues of head or bone structures of skull could have intracranial injuries which could be treated only at the stage of tertiary medical care.

[Surgical tactics in gunshot wounds of the spine and spinal cord].

Based on literature data and personal experiences with treatment of patients with this pathology the author considers the sequence of diagnostic measures, describes his experience with contrast examinations of the vertebral canal in the acute period. The volume of the infusion-transfusion therapy was determined. Details of the surgical tactics were outlined with a reference to the character of the injury.

[Status of the kallikrein-kinin system in experimental disorders of cerebral circulation].

On a model of acute impairment of the cerebral circulation the authors studied (using the conventional methods) the status of various components of the kallikrein-kinin system of the blood and tissues during a period of 7 days. It has been established that the kallikrein-kinin system has periods of activation 1-6 hours and 1-3 days and a period of "inhibition" 12 hours after the beginning of the experiment. These data may be used in clinical practice for the treatment of patients with cerebrovascular disturbances.

[Organization of stress fibrils in cultured fibroblasts studied by using an actin filament-fragmenting protein].

Earlier we isolated a 1:1 complex of 90 kD-protein and actin from bovine brain. This complex was able to fragment actin filaments. Effects of this complex on the cytoskeleton of mouse and quail embryo fibroblasts are described.

[Study of a protein complex from the brain which reduces actin viscosity. II. The complex inhibits elongation of actin filaments at the end preferable for polymerization and fragments the filaments].

Functional properties of the protein complex from bovine brain that shortens actin filaments are described. In the presence of Ca2+ complex shortens actin filaments and increases the initial rate of actin polymerization. In the absence of free calcium ions the complex loses its accelerating effect on actin polymerization, but still possesses actin filament shortening activity.

[Study of a protein complex from the brain which reduces actin viscosity. I. Composition and various properties of the complex].

The method of isolation from bovine brain of a preparation containing 90 kDa- and 42 kDa-proteins is described. This preparation shortens actin filaments and therefore decreases viscosity of F-actin. The 42 kDa-component was identified as actin by one-dimensional peptide mapping.

[Postoperative recurrences of neurologic syndromes of lumbar osteochondrosis and their surgical treatment].

The authors analyse the clinical forms of recurrent neurological syndromes of lumbar osteochondrosis which developed in 6.2% of the patients operated on through a posterior approach. The recurrence of the process was caused by a progressive degenerative-dystrophic process in an earlier operated on intervertebral disc in 40 (50%) patients, a pathological condition of an intervertebral disc adjacent to one which had been operated on in 29 (36.

[Esterase activity of the mitochondria oligomycin-sensitive ATPase complex].

It was found that mitochondrial oligomycin-sensitive ATPase (OS-ATPase) possesses the esterase activity with respect to some carboxylic acid esters with phenols and arylalcane alcohols. The substrate specificity of the esterase found was studied. The effects of some inhibitors and activators of ATPase on the enzyme activity were demonstrated.