Publications by authors named "Verkhliutov V"

Pseudowords and words of "animate" and "inanimate" categories were shown to healthy young adults (14 women and 9 men) in three series. In the first series, subjects were just reading presented verbal stimuli (words and pseudowords), in the second series, they had to click a mouse button in response to presentation of a word, and in the third series they clicked a button when pseudowords were presented. Presentation of words and pseudowords caused desynchronization of the alpha rhythm and synchronization of the theta rhythm.

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In 10 healthy volunteers, brain tomograms were recorded using an fMRI scanner with a 3T-field magnet. Emotionally neutral and emotionally involving videos were used for stimulation. Registration consisted of seven series: two series of viewing a fixation point and two kinds of video clips, one series of viewing of a succession of two types of video clips, two series of watching videos with subsequent recall, and two series of viewing the fixation point followed by recall of content online.

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The 15 healthy volunteers EEG from 28 channels was recorded during the presentation of visual stimuli in the form of face and building images. The stimuli were presented in two series. The first series consisted of 60 face and 60 building images presented in random order.

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Twenty seven right-handed subjects aged 7-30 years with the attention deficit/hyperactivity disorder (ADHD) were exposed to standard MRI examination. From them, 14 were younger than 13 years old. The volumes of lateral ventricles were measured using T1-weighted MR-images of the sagittal brain sections to within 3 mm3.

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The proposed modification of boundary element method (BEM) makes it possible to solve direct EEG problem taking into account individual head geometry. This modification decreases computational cost thus enabling practical usage of BEM for localization of EEG dipole sources. The method developed was applied for error estimation of dipole localization using spherical approximation with the aid of BESA software.

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The influence of the thickness and specific resistance of the brain tissues and its surrounding coverings, brain sulci and anisotropy of white matter electric conductivity on the EEG potentials were modeled. The finite element method was used for simulation, which is realized in the Femlab module. During the comparison of two models with different thickness of the layers was shown the change of potentials by 40% for scull, which thickness varied by 9 mm, and for the gray matter and spinal fluid the change of potentials amounted to 15% by 3 mm variable thickness.

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In 12 healthy subjects and 9 schizophrenic patients in the background conditions (with eyes closed) EEG was recorded from 16 standard derivations (10-20 system) during 3 min. The record underwent the spectral analysis detecting alpha- and theta-frequency bands. After the preliminary narrow band filtration for the main frequencies the sources of the spontaneous rhythms were localized.

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Exact localization of equivalent current dipoles (ECD) was obtained by combining the EEG and the MRI mapping allowing to trace the ECG displacement over the cortex. The data obtained corroborate localization of the alpha-rhythm ECD in the Gyrus Calcarina: the human primary visual cortex. Successive shifts of the ECD over this area during generation of each alpha-wave, were revealed.

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In 11 subjects the dynamic localization (with 2-ms step) of the equivalent current dipole of alpha rhythm during travelling alpha waves was studied using one-dipole 3-layered spherical head model and MRI. The dipole was localized in the occipital cortex and during the development of a single alpha wave it shifted in one or another direction while dipole's moment revealed fan-like rotation mainly in sagittal and horizontal planes. The results obtained indicate changing localization of the alpha-rhythm source in the region corresponding to striate cortex.

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In computer-controlled experiments the visual illusions were studied which appeared in human subjects under conditions of diffuse rhythmic photostimulation through the closed eyes with the individual dominant alpha-rhythm frequency. A significant correlation was demonstrated between the type of experienced illusion (or its absence) and the trajectory of the alpha-wave travelling in the prestimulation and stimulation periods.

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The model of the alpha-rhythm was studied which consisted of a set of elementary dipoles. The dipoles were fixed normally to the surfaces of a cruciform structure which imitated the structure of the visual cortex. The magnitude of dipole moments varied according to the sinusoidal low.

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Using one-channel SQUID biomagnetometer alpha rhythm was recorded in five healthy men and eight healthy women. Maps of distribution of maximum values of mean MEG amplitudes were analyzed. Most frequently MEG maxima predominated in the parietal parts of the head.

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