Publications by authors named "Verina Logito"

Introduction: Corona Virus Disease-19 (COVID-19) is a disease caused by Severe-Acute-Respiratory-Syndrome-Coronavirus-2 (SARS-CoV-2). The most reliable and widely accepted method for diagnosing this infection, despite facing various challenges, is the Reverse Transcription Polymerase Chain Reaction (RT-PCR) method, which utilizes nasopharyngeal swab sample. Reverse-transcription loop mediated isothermal amplification (RT-LAMP) is a simpler nucleic acid amplification method compared to the RT-PCR method.

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Introduction: Laboratory examination is extremely important in handling the COVID-19 pandemic. In the first era of the pandemic, the molecular and antigen tests were limited. Hence, at that time, it was necessary to carry out antibody Rapid Diagnostic Tests (RDT).

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Introduction: Human immunodeficiency virus (HIV) infection is a risk factor for the occurrence of a large of (Mtb) antigen load in the body. The antigens cocktail namely early secretory antigenic target protein 6-kDa (ESAT-6), Culture filtrate protein 10 kDa (CFP-10), and protein 64 (MPT-64) are secreted by Mtb during replication, hence, their concentration increase in patients with active Tuberculosis (TB). This increased levels facilitates their entry into the systemic circulation, followed by secretion by the glomerulus into the urine.

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Article Synopsis
  • Systemic Sclerosis related Interstitial Lung Disease (SSc-ILD) is a serious condition with high morbidity and mortality, but diagnostic tools like Thorax High-Resolution Computed Tomography (HCRT) are not always available in healthcare facilities.
  • A retrospective study examined the effectiveness of specific autoantibody tests (anti-topoisomerase-1, anti-Th/To, and anti-fibrillarin) for diagnosing SSc-ILD, analyzing data from 74 patients diagnosed with SSc using standard criteria.
  • Results showed varying sensitivities and specificities for each autoantibody, with a combination yielding high sensitivity but low specificity; combining these tests with HCRT may enhance patient detection rates.
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