Drug-related pityriasis rubra pilaris with acantholysis.

Introduction: Acantholysis is rarely reported histological feature of Pityriasis rubra pilaris (PRP), recently recognized as having diagnostic specificity for differentiating PRP from psoriasis.

Case Report: Adult male patient one week after the introduction of simvastatin had experienced pruritic erythemo-squamous eruption on head and upper trunk that in a month progressed to erythrodermia, with islands of sparing. Histological picture combined pemphigus-like acantholysis with alternating hyper- and parakeratosis, follicular plugs and dermal inflammation, and confirmed the clinical diagnosis of classic adult type 1 PRP.

[Viral form of hemophagocytic syndrome with erythrodermal clinical picture--case report].

Introduction: Hemophagocytic syndrome is patophysiological entity with proliferation and over-activation of macrophages, with hemophagocytosis and production of proinflammatory cytokines. It arises as hereditary forms, or acquired, during viral, autoimmune or malignant diseases, and is usually a disorder with fulminant course and high incidence of lethal outcome. The precise mechanism is not resolved; it is a consequence of cytokine storm generated by over-activated T cells and macrophages, due to defects in T cellular cytototoxic function and inadequate down-regulation of immune response.

[Presentation of the Department and Clinic of Dermatology and Venereology].

THE DEPARTMENT OF DERMATOVENEROLOGY: The Department of Dermatovenereology was established in 1963, as part of the Department of Internal Medicine with Professor Dimitrije Stanulović as its head. Since 1983, it has been an independent department of the Faculty of Medicine in Novi Sad. DEPARTMENT ACTIVITIES: The Department participates in undergraduate education of medical and dentistry students (serbian and english language), advanced training of graduate students specializing in dermatovenereology, general medicine, urgent and occupational medicine, pediatrics and subspecialists of oncology.

[Papular-purpuric gloves and socks syndrome--a case report].

Introduction: Papular-purpuric gloves and socks syndrome is a rare manifestation associated with acute seronegative arthritis and skin lesions. It is triggered by a viral infection, most commonly by Human parvovirus B19 or Coxsackie group of viruses, but precise viral diagnosis is not obtained in all cases.

Case Report: A 54-year old male patient experienced sudden, intense pain and swelling in the carpal area of his left hand.

Erythema infectiosum in children. A Clinical study.

Erythema infectiosum is a childhood illness characterized by mild constitutional symptoms and a blotchy or maculopopular lacy rash on the cheeks (slapped - cheek) spreading primarily to the extremities and trunk. The disease is caused by human parvovirus B19. Erythema infectiosum epidemics occur in a cyclic fashion, mostly during winter and spring months.

[Some psychological characteristics of children and adolescents with vitiligo--our results].

Introduction: Numerous studies have characterized patients with chronic skin disease as psychologically vulnerable, mainly due to the fact that their condition affects their social relations and all other aspects of life. The purpose of this work was to determine whether there are significant differences in the level of anxiety, severity of depressive symptoms, and presence of stressful life events between adolescent patients with vitiligo and healthy peers.

Material And Methods: 33 patients with vitiligo aged 10-15 years, and a control group of 60 healthy subjects of the same age, were included in this prospective study.

[Autoantibodies in children with vitiligo].

Introduction: Vitiligo is an acquired, sometimes familial skin depigmentation disorder. In about half of patients it occurs before the age of twenty. The aim of this study was to investigate the incidence and significance of autoantibodies (AT) and associated autoimmune and endocrine diseases in children with vitiligo, in relation to adults with vitiligo and children without vitiligo.

Contact allergy to Compositae plants in patients with atopic dermatitis.

To investigate the frequency of Compositae sensitivity is one of the most important goals of current dermatology and allergology. We have patch tested 30 adult patients suffering from "extrinsic" atopic dermatitis with sesquiterpene lactone mix and Compositae mix including Compositae mix individual ingredients, extracts of arnica (Arnica montana), chamomile (Chamomilla recutita), tansy (Tanacetum vulgare), fever few (Tanacetum parthenium) and yarrow (Achillea millefolium) as well as with specific series for patients with atopic dermatitis. All allergens were purchased from Hermal-Trolab (Reinbek, Germany).

[Low level laser irradiation and its effect on repair processes in the skin].

Introduction: Application of laser beams for therapeutic purposes is of relatively recent date, but today there is no field of medicine where lasers cannot be used.

Physical Characteristics Of Laser Radiation: Laser radiation is a type of electromagnetic radiation with some specific characteristics such as coherence, monochromaticity and parallelity.

Types Of Laser Devices: Nowadays, there are many laser devices on the market used in medicine and dentistry.

[Vitiligo in childhood].

Introduction: Vitiligo is an acquired, sometimes familial skin depigmentation disorder due to selective destruction of melanocytes. Vitiligo is primarily a disease of the young; in about half of patients it occurs before the age of twenty. The aim of this study was to investigate some epidemiological and clinical characteristics of vitiligo in children, in relation to adults with vitiligo and children without vitiligo.

[Psoriasis and autoimmune skin disorders].

Introduction: Presuming that psoriasis is an autoimmune skin disease, the aim of this study was to establish its association with other autoimmune skin diseases. The material was obtained at the Dermatovenereological Clinic--Clinical Center Novi Sad.

Material And Methods: This 10-year retrospective study (1990-1999) included 1743 psoriasis patients.