Colloids Surf B Biointerfaces
November 2019
Multifunctional liposomes incorporating β-sitosterol were developed for delivery of gentisic acid (GA). The interactions of both compounds with phospholipid bilayer were interpreted viaeffects of different β-sitosterol content (0, 20 and 50 mol %) and different gentisic acid to lipid ratio (n/n from 10 to 1) on membrane fluidity and thermotropic properties. Multilamellar vesicles of phosphatidylcholines (with size range between 1350 and 1900 nm) effectively encapsulated GA (54%) when n/n was higher than 0.
View Article and Find Full Text PDFIn this work chitosan microbeads were prepared by emulsion technique and loaded with thyme polyphenols by diffusion from an external aqueous solution of Thymus serpyllum L. The effects of concentrations of chitosan (1.5-3% (w/v)) and GA (glutaraldehyde) (0.
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