Publications by authors named "Vergez S"
Article Synopsis
- Mild cognitive impairment and early-stage dementia are often underdiagnosed, leading to increased healthcare costs; this study aims to address this gap by using patient-nurse conversations recorded in home healthcare settings to develop an AI tool for early detection of cognitive decline.
- The research involved analyzing audio from conversations of 47 patients, identifying key linguistic features related to cognitive decline, and comparing the effectiveness of a speech processing algorithm to traditional electronic health record data.
- Results showed that the combined approach of using verbal communication and EHR data significantly outperformed either method alone, highlighting that certain speech patterns can predict cognitive decline, thus potentially improving patient care and reducing emergency healthcare visits.
Objectives: As artificial intelligence evolves, integrating speech processing into home healthcare (HHC) workflows is increasingly feasible. Audio-recorded communications enhance risk identification models, with automatic speech recognition (ASR) systems as a key component. This study evaluates the transcription accuracy and equity of 4 ASR systems-Amazon Web Services (AWS) General, AWS Medical, Whisper, and Wave2Vec-in transcribing patient-nurse communication in US HHC, focusing on their ability in accurate transcription of speech from Black and White English-speaking patients.
View Article and Find Full Text PDFExpert perspectives for transoral robotic versus laser surgery for supraglottic carcinomas.
Eur Arch Otorhinolaryngol
November 2024
Article Synopsis
- The study aimed to gather insights from international experts on the efficacy and challenges of two minimally invasive surgical techniques, transoral laser microsurgery (TLM) and transoral robotic surgery (TORS), for treating supraglottic laryngeal tumors.
- A survey was conducted with 27 head and neck surgeons, finding that TLM generally took less setup time compared to TORS, although both techniques faced concerns about bleeding during surgery, particularly with TLM.
- Experts viewed TLM and TORS as largely equal in effectiveness, but noted that TORS offered better control over bleeding and improved visibility during the procedure.
Article Synopsis
- Salivary gland Secretory Carcinoma (SC) is a rare tumor first described in 2010; a study analyzed 108 cases from the REFCOR database to evaluate diagnosis, treatment, and survival rates up to July 2021.
- MRI was found to be ineffective for diagnosing malignancy, and while 79% of patients received a diagnosis after two histological readings, 21% needed molecular testing for confirmation.
- Results showed high survival rates, with 91.4% overall survival and 89% recurrence-free survival at five years, suggesting a generally positive prognosis for SC patients.*
Introduction: Salivary carcinomas of the tongue represent a therapeutic challenge as their radical excision is particularly mutilating. We aimed to study the oncologic and functional outcomes of advanced stages salivary carcinomas of the tongue.
Materials And Methods: This retrospective multicentric study, based on the French national network on rare head and neck cancers (REFCOR), included all patients with a T3-T4 salivary carcinoma of the tongue, diagnosed between January 2009 and December 2018.
Objectives: The management of the facial nerve (FN) is a major issue in parotid cancer, especially when there is no preoperative facial palsy and FN invasion is discovered intraoperatively. The aim of this study was to assess the impact of FN resection in patients with parotid cancer abutting the FN, without pretreatment facial palsy, using a propensity score matching.
Materials And Methods: Data from all patients treated between 2009 and 2020 for a primary parotid cancer abutting or invading the FN but without pretreatment facial palsy were extracted from the national multicentric REFCOR database.
Article Synopsis
- Salivary carcinomas of minor salivary glands, particularly in the tongue, are rare tumors that may require surgery and/or (chemo-)radiotherapy for treatment.
- A study involving 103 patients diagnosed between 2009 and 2018 found that the most common types were adenoid cystic and mucoepidermoid carcinomas, with surgery being the primary treatment for most cases.
- Results indicated that 5-year overall survival was 84.7%, while event-free survival was lower at 38.6%; nonsurgical treatment, alcohol use, and tumor location negatively impacted event-free survival, while nodal positivity was a key factor affecting overall survival.
Background: We developed the Hospital-to-Home-Health Transition Quality (H3TQ) Index for skilled home healthcare (HH) agencies to identify threats to safe, high-quality care transitions in real time.
Objective: Assess the validity of H3TQ in a large sample across diverse communities.
Research Design: A survey of recently hospitalized older adults referred for skilled HH services and their HH provider at two large HH agencies in Baltimore, MD, and New York, NY.
Objective: To elucidate the prognostic implications of mucosal and deep margin distances in oral tongue squamous cell carcinoma (OTSCC), and to assess a different margin cut-off value in T1-T2 versus T3-T4 tumors.
Methods: This single-center retrospective study included 223 patients who received surgery for a primary OTSCC between January 2017 and December 2021.
Results: Multivariable analysis showed that deep margin distance ≥3 mm in T1-T2 tumors and ≥5 mm in T3-T4 tumors was significantly associated with better RFS and OS.
Heart failure (HF) affects six million people in the U.S., is associated with high morbidity, mortality, and healthcare utilization.
View Article and Find Full Text PDFBackground: Transoral robotic surgery (TORS) opens new perspectives. We evaluated the outcomes for patients having undergone TORS after previous radiotherapy.
Methods: A retrospective multicenter study (n = 138) in a previously irradiated area between 2009 and 2020.
Background: Rare cancers constitute less than 10% of head and neck cancers and lack sufficient evidence for standardized care. The French Rare Head and Neck Cancer Expert Network (REFCOR) as established a national database to collect data on these rare cancers. This study aims to describe patient and tumour characteristics in this database.
View Article and Find Full Text PDFBackground: Skilled home healthcare (HH) provided in-person care to older adults during the COVID-19 pandemic, yet little is known about the pandemic's impact on HH care transition patterns. We investigated pandemic impact on (1) HH service volume; (2) population characteristics; and (3) care transition patterns for older adults receiving HH services after hospital or skilled nursing facility (SNF) discharge.
Methods: Retrospective, cohort, comparative study of recently hospitalized older adults (≥ 65 years) receiving HH services after hospital or SNF discharge at two large HH agencies in Baltimore and New York City (NYC) 1-year pre- and 1-year post-pandemic onset.
Objectives: To analyse prognostic factors and survival outcomes of malignant tumors of the external auditory canal, to investigate the role of regional surgery, and adjuvant radiotherapy in early stages and to investigate the role of surgery in operable T4 stage.
Setting: A retrospective analysis was conducted on all patients prospectively included in the national database of the French Expertize Network for Rare ENT Cancers (REFCOR) from January 2000 to December 2016.
Participants: 103 patients from 19 reference centers were included.
Introduction: Laryngeal chondrosarcoma (LCS) is a rare tumor of slow evolution whose treatment is poorly codified. For a long time, a radical treatment by total laryngectomy (TL) was proposed. More recent studies tend to propose a conservative surgical approach of the larynx.
View Article and Find Full Text PDFArticle Synopsis
- Researchers wanted to see how well a special swallowing test called VFSS can find leaks in the throat after surgery to remove parts of the throat and voice box.
- They looked at 248 patients who had this surgery and took the swallowing test about a week to two weeks later.
- The test was pretty good at spotting leaks; it helped prevent future problems for many patients who had a positive test result.
Evaluation of the results of laryngeal transplantation (LT) in humans. Analysis of 3 bibliographic databases with the keywords "larynx, transplantation, autograft". In total, 626 abstracts were read and 25 articles selected.
View Article and Find Full Text PDFArticle Synopsis
- There is currently no reliable biomarker for predicting the effectiveness of EGFR inhibitors in head and neck squamous cell carcinoma (HNSCC), leading researchers to investigate afatinib, a promising treatment.
- In a trial with 61 patients, afatinib showed a high metabolic response, with responders demonstrating specific biomarker expressions (higher pERK1/2 and lower pHER4 and pRB1 levels).
- Further analysis indicated that responders had more tumor-infiltrating B cells, while non-responders had an overrepresentation of NF-kappa B signaling in their gene expression, suggesting potential new biomarkers for afatinib efficacy that require more research.*
Salivary gland cancer: Recommendations by formal consensus, for the French Network of Rare Head and Neck Tumors (REFCOR).
Eur Ann Otorhinolaryngol Head Neck Dis
January 2024
Systemic therapies for salivary gland cancer: Adenoid cystic carcinoma. REFCOR recommendations by the formal consensus method.
Eur Ann Otorhinolaryngol Head Neck Dis
September 2024
Objective: To determine the therapeutic indications for systemic medical treatment in the management of adenoid cystic carcinoma (ACC) according to the clinical situation.
Materials And Methods: The French Network of Rare Head and Neck Tumors (REFCOR) formed a steering group, which drafted a narrative review of the literature published on Medline and proposed recommendations. The level of adherence to the recommendations was then assessed by a rating group, according to the formal consensus method.
2023: First laryngeal transplantation in France by the "ECLAT" group!
Eur Ann Otorhinolaryngol Head Neck Dis
January 2024
Cytopathological analysis of salivary gland cancer: REFCOR recommendations by the formal consensus method.
Eur Ann Otorhinolaryngol Head Neck Dis
March 2024
Objective: To determine the indications for fine-needle cytology and the modalities of frozen section pathological analysis in the management of salivary gland cancer.
Material And Methods: The French Network of Rare Head and Neck Tumors (REFCOR) formed a steering group who drafted a narrative review of the literature published on Medline and proposed recommendations. The level of adherence to the recommendations was then assessed by a rating group according to the formal consensus method.
Surgery of sublingual and minor salivary gland cancer: REFCOR recommendations by the formal consensus method.
Eur Ann Otorhinolaryngol Head Neck Dis
November 2024
Objective: To determine the indications and modalities for resection in the management of primary sublingual and minor salivary gland cancer, and the specific features of each primary location.
Material And Methods: The French Network of Rare Head and Neck Tumors (REFCOR) formed a steering group who drafted a narrative review of the literature published on Medline and proposed recommendations. The level of adherence to the recommendations was then assessed by a rating group, according to the formal consensus method.
Systemic therapies for salivary gland carcinoma (excluding adenoid cystic carcinoma): REFCOR recommendations by the formal consensus method.
Eur Ann Otorhinolaryngol Head Neck Dis
September 2024
Objective: To determine the therapeutic indications for systemic medical treatment in the management of salivary gland carcinoma (excluding adenoid cystic carcinoma) according to the clinical situation.
Materials And Methods: The French Network of Rare Head and Neck Tumors (REFCOR) formed a steering group who drafted a narrative review of the literature published on Medline and proposed recommendations. The level of adherence to the recommendations was then assessed by a rating group, according to the formal consensus method.