Publications by authors named "Vergara-Ortega D"
Article Synopsis
- * Young women (ages 18-24) had a higher HSV-2 seroprevalence (12.1%) compared to adolescents (4.3%), with frequent alcohol consumption also linked to a higher risk of infection.
- * Although vaginal HSV-2 shedding peaked in the third trimester, the difference wasn't statistically significant; nonetheless, this increases the risk of neonatal herpes from vertical transmission during pregnancy.
[High seroprevalence of syphilis and genital herpes in migrants in transit in Chiapas, MexicoAlta soroprevalência de sífilis e herpes genital em migrantes em trânsito por Chiapas, México].
Rev Panam Salud Publica
April 2023
Article Synopsis
- * Conducted in 2021-2022, the research involved 462 migrants who filled out questionnaires and underwent blood tests to detect these infections, revealing a 29.9% prevalence for HSV-2 and 4.5% for syphilis, particularly higher in men.
- * The findings show that both infections are highly present among the migrant population, highlighting the need for targeted prevention and treatment efforts, especially considering their unique vulnerabilities related to sexual behavior.
Article Synopsis
- * Study findings identify various risk factors for syphilis among MSM, including low economic status, use of inhalant drugs, and specific sexual practices.
- * There is a growing need for targeted prevention efforts in Mexico to address both syphilis and HIV among MSM, particularly considering the increasing prevalence observed in more recent years.
Syphilis is a sexually transmitted disease that has become a public health problem, especially in vulnerable populations. A systematic review and time-free meta-analysis of the publications on the molecular detection of syphilis and mutations associated with antibiotic resistance, CORE group, and syphilis genotypes in PubMed databases, Scielo, and Cochrane was performed, and the last search was conducted in June 2022. Proportions were calculated, and standard errors and confidence intervals were reported for all results of interest.
View Article and Find Full Text PDFMuch is known about the natural history of syphilis; however, less is known about the immune response against it, and even less is known about people living with HIV (PLWH). Due to the lack of an animal model to study host-pathogen interactions, it remains unclear how the host eliminates the bacteria. Here, we attempt to elucidate the immune response against infection by summarizing all the reported data in a systematic review.
View Article and Find Full Text PDFBackground: HIV incidence can be estimated with cross-sectional studies using clinical, serological, and molecular data. Worldwide, HIV incidence data in only men who have sex with men (MSM) are scarce and principally focus on those with healthcare or under treatment. However, better estimates can be obtained through studies with national representativeness.
View Article and Find Full Text PDFThis study shows the relative quantification of HSV-2 by qPCR, using the MIQE Guidelines. The reaction efficiency was evaluated, and the relative quantification used the R = 2 method. The relative quantification of HSV-2 was conducted with anal and genital samples from men who have sex with men (MSM), living with HIV.
View Article and Find Full Text PDFObjective: To determine HSV-2 seroprevalence, risk factors, and antibody avidity among a sample of Mexican pregnant women.
Material And Methods: The avidity test was standardized with different urea concentrations and incubation times; the cut-off point was calculated to determine the low avidity (early infection). IgG antibodies against HSV-2 were detected from pregnant and postpartum women from Morelos, Mexico, and the avidity test was performed to positive samples.