Publications by authors named "Verena Gruber"

Article Synopsis
  • The study investigates the role of a specific signaling axis in diffuse large B cell lymphoma (DLBCL), finding significantly higher expression in tumor cells compared to healthy controls, which correlates with worse clinical outcomes.
  • Researchers observed that levels of this axis decreased in patients who achieved remission after treatment, linking it to lymphoma infiltration in bone marrow biopsies.
  • Additionally, they tested three CXCR4 antagonists, including a newly synthesized compound (WK1), discovering that WK1 has stronger effects on inducing cell death and reducing key gene expressions related to cancer progression, suggesting its potential as a treatment target for aggressive lymphomas.
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Health care workers (HCW) are at increased risk for acquisition of hepatitis B virus (HBV) infection from occupational exposure. This can be prevented by active immunization. We performed a retrospective chart review of HCW who were persistent low (anti-HBs antibody values <100 U/L) or non responders (<10 U/L) after 6 active immunizations and demonstrate successful immunization (anti-HBs ≥100 U/l) after a total of 8-14 vaccine doses in 13 such HCW by use of various vaccination schedules.

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