Publications by authors named "Verena E Deutschmeyer"
Article Synopsis
- SIAH3, a member of the SIAH family in humans, is often silenced in various cancers like melanoma and lung adenocarcinoma, leading to worse survival for patients.
- Inducing SIAH3 expression can decrease cancer cell growth and trigger cell death, as it shifts cellular energy production from aerobic metabolism to glycolysis.
- SIAH3 is found in mitochondria and interacts with proteins related to mitochondrial function and other ubiquitin ligases, suggesting it plays a role as a tumor suppressor by regulating metabolism.
The ZAR1 protein in cancer; from epigenetic silencing to functional characterisation and epigenetic therapy of tumour suppressors.
Biochim Biophys Acta Rev Cancer
December 2020
ZAR1, zygote arrest 1, is a zinc finger protein (C-terminus), which was initially identified in mouse oocytes. Later it was found that its expression is present in various human tissues e.g.
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