Publications by authors named "Verdonck P"

Introduction: The centralisation of care for trauma patients in trauma centres, alongside the creation of inclusive trauma networks, has proven to reduce mortality. In Europe, such structured trauma programs and trauma networks are in development.

Objective: To describe the aetiology and evolution of in-hospital mortality in a developing European level 1 trauma centre, to determine the early effect of trauma care reorganisation on mortality and to identify the areas for future investments in trauma care.

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  • The study aimed to evaluate the outcomes and patient characteristics of those who underwent extracorporeal cardiopulmonary resuscitation (ECPR) for out-of-hospital cardiac arrest, as well as the associated costs for both patients and the Belgian healthcare system.
  • Conducted at Antwerp University Hospital, the research analyzed medical records from 2018 to 2020, tracking patient outcomes and costs using a detailed micro costing technique.
  • Results showed that out of 65 patients, 58% died within a week and only 18.5% survived one year with good neurological outcomes, revealing a significant economic impact of €255,250 per survivor, underscoring the need for careful patient selection in ECPR procedures
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  • - The ATLS (2018) guidelines recommend providing supplemental oxygen to all severely injured trauma patients to prevent low blood oxygen levels, but this practice may risk causing excessive oxygen levels, which could lead to increased mortality and complications.
  • - A survey of 707 clinicians, predominantly from Denmark and mostly physicians, revealed that 73% do not believe supplemental oxygen should be given universally to severely injured trauma patients without considering their oxygen saturation levels.
  • - Respondents indicated that the average initial oxygen dosage for trauma patients with normal oxygen saturation was 0 liters per minute, with 58% choosing not to give supplemental oxygen at all, and the lowest acceptable oxygen saturation target was 94%.
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  • Measuring spontaneous swallowing frequencies (SSF) and coughing frequencies (CF) can provide insights into swallowing function and pneumonia risk in patients, especially in ICU settings.
  • Current technologies for measuring SSF and CF are complex, leading to a need for simpler methods that are easy to implement in clinical practice.
  • A study developed a low-complexity system using medical-grade sensors to accurately detect swallowing and coughing, achieving decent sensitivity and specificity in distinguishing these actions from other movements.
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  • Multiple studies highlight that early warning systems (EWS) improve clinical outcomes and patient safety, but integrating them into practice faces challenges due to their simplification of complex health conditions into single scores.
  • * Despite the promise of wearable medical technologies for continuous monitoring, questions remain about their reliability compared to traditional methods.
  • * A study was conducted to assess the accuracy of data from the Vivalink Cardiac patch against the standard ECG monitoring in ICU patients, focusing on heart and respiratory rate measurements.
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Introduction: A considerable percentage of daily emergency calls are for nursing home residents. With the ageing of the overall European population, an increase in emergency calls and interventions in nursing homes (NH) is to be expected. A proportion of these interventions and hospital transfers may be preventable and could be considered as inappropriate by prehospital emergency medical personnel.

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The remote monitoring of vital signs via wearable devices holds significant potential for alleviating the strain on hospital resources and elder-care facilities. Among the various techniques available, photoplethysmography stands out as particularly promising for assessing vital signs such as heart rate, respiratory rate, oxygen saturation, and blood pressure. Despite the efficacy of this method, many commercially available wearables, bearing Conformité Européenne marks and the approval of the Food and Drug Administration, are often integrated within proprietary, closed data ecosystems and are very expensive.

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The European Trauma Course (ETC) exemplifies an innovative approach to multispecialty trauma education. This initiative was started as a collaborative effort among the European Society for Emergency Medicine, the European Society for Trauma and Emergency Surgery, and the European Society of Anaesthesiology under the auspices of the European Resuscitation Council. With the robust support of these societies, the project has evolved into the independent European Trauma Course Organisation.

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Key Clinical Message: This case report supports that trauma can rarely cause thrombotic microangiopathy (TMA). Early recognition is important due to a high mortality of untreated TMA, but diagnosis can be delayed by attributing lab abnormalities as due to blood loss.

Abstract: Major trauma can provoke coagulopathy, ranging from hypo- to hypercoagulation.

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Background: Trauma is the leading cause of death in patients <45 years living in high-resource settings. However, penetrating chest injuries are still relatively rare in Europe - with an upwards trend. These cases are of particular interest to emergency medical services (EMS) due to available invasive treatment options like chest tube placement or resuscitative thoracotomy.

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Volatile anaesthetics are potent greenhouse gasses but contemporary workstations enable considerable savings while improving patient safety. Institutions may provide this technology to reduce the ecological footprint but proper training and motivation is required to maximize their ecologic and financial benefit. This study aims to compare the sevoflurane consumption of 22 anaesthesiologists in a medium sized hospital 4 years after flow-i workstations (Getinge, Sweden) entered into service, in three airway approaches: intubated patients, laryngeal mask ventilation, and mask anaesthesia.

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Left ventricular flow is intrinsically complex, three-dimensional and unsteady. Its features are susceptible to cardiovascular pathology and treatment, in particular to surgical interventions involving the valves (mitral valve replacement). To improve our understanding of intraventricular fluid mechanics and the impact of various types of prosthetic valves thereon, we have developed a custom-designed versatile left ventricular phantom with anatomically realistic moving left ventricular membrane.

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Background: The aims of this study were to investigate the evolution of the transprosthetic pressure gradient and effective orifice area (EOA) during dynamic bicycle exercise in bileaflet mechanical heart valves and to explore the relationship with exercise capacity.

Methods: Patients with bileaflet aortic valve replacement (n = 23) and mitral valve replacement (MVR; n = 16) prospectively underwent symptom-limited supine bicycle exercise testing with Doppler echocardiography and respiratory gas analysis. Transprosthetic flow rate, peak and mean transprosthetic gradient, EOA, and systolic pulmonary artery pressure were assessed at different stages of exercise.

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Background: Unrecognised endotracheal tube misplacement in emergency intubations has a reported incidence of up to 17%. Current detection methods have many limitations restricting their reliability and availability in these circumstances. There is therefore a clinical need for a device that is small enough to be practical in emergency situations and that can detect oesophageal intubation within seconds.

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Penetrating and blunt trauma to the neck: clinical presentation, assessment ana emergency management. In Belgium, and even in Western Europe, penetrating and blunt injury to the neck is relatively uncommon in both the civilian and military populations. Pre-hospital and emergency assessment and management will therefore always prove challenging, as individual exposure to this specific type of injury remains low.

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We demonstrate the impact of reducing agents for Chemical Vapor Deposition (CVD) and Atomic Layer Deposition (ALD) of WS2 from WF6 and H2S precursors. Nanocrystalline WS2 layers with a two-dimensional structure can be obtained at low deposition temperatures (300-450 °C) without using a template or anneal.

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Purpose: Symmetric-tip dialysis catheters have become alternative devices because of low access recirculation and ease of tip positioning. Flow characteristics of three symmetric catheters were compared based on computational fluid dynamics (CFD) as they relate to catheter function.

Materials And Methods: In Palindrome, GlidePath, and VectorFlow catheters, a computational fluid dynamics-based approach was used to assess (i) regions of flow separation, which are prone to thrombus development; (ii) shear-induced platelet activation potency; (iii) recirculation; and (iv) venous outflow deflection.

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Article Synopsis
  • Carotid artery stenting (CAS) is a procedure for treating severe carotid artery blockages in high-risk patients, and the study evaluates a new virtual tool to help improve patient-specific stent deployment.
  • The research involved two patients and assessed stent placement using numerical models and post-operative imaging to validate results, focusing on critical parameters that relate to stent success.
  • Findings indicate the virtual environment can aid specialists by providing insights into stent behavior and potential complications, especially in complex cases requiring precise stent design and positioning.
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Background: During robot assisted laparoscopic radical prostatectomy (RALRP), a CO2 pneumoperitoneum (CO2PP) is applied and the patient is placed in a head-down position. Intracranial pressure (ICP) is expected to acutely increase under these conditions. A non-invasive method, the optic nerve sheath diameter (ONSD) measurement, may warn us that the mechanism of protective cerebrospinal fluid (CSF) shifts becomes exhausted.

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The aim of this study was to reconcile some of our own previous work and the work of others to generate a physiologically realistic numerical simulation environment that allows to virtually assess the performance of BMHVs. The model incorporates: (i) a left ventricular deformable model to generate a physiological inflow to the aortic valve; (ii) a patient-specific aortic geometry (root, arch and descending aorta); (iii) physiological pressure and flow boundary conditions. We particularly studied the influence of downstream geometry, valve size and orientation on leaflet kinematics and functional indices used in clinical routine.

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Self-assembled monolayers (SAMs) from an 11-cyanoundecyltrichlorosilane (CN-SAM) precursor were deposited on porous SiCOH low-k dielectrics with three different pore radii, namely, 1.7, 0.7, and lower than 0.

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A completely different treatment approach was chosen for 2 patients with unilateral diaphragmatic paralysis and complaints of dyspnea despite similar anatomic and physiologic abnormalities. These decisions were supported by results obtained by functional respiratory imaging (FRI). FRI generated functional information on lobar ventilation and local drug deposition.

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