Publications by authors named "Veraldi S"
Acne and acne sequelae can have an important impact on patients' quality of life, affecting interpersonal relationships and social functioning. Acne-induced scars (AIS) and acne-induced macular hyperpigmentation (AIH), in particular, are a major concern for patients with acne, as their management is challenging and often unsatisfactory. Retinoids are considered the mainstay of acne treatment because of their action on multiple pathogenetic factors, and there is increasing evidence that they can also improve AIS and AIH.
View Article and Find Full Text PDFLiver transplantation (LTx) is increasingly used in Urea Cycle Defects (UCDs) to prevent recurrent hyperammonemia and related neurological irreversible injury. Among UCDs, argininosuccinate lyase deficiency (ASLD) has a more complex phenotype than other UCDs, with long-term neurocognitive deficits. Therefore, the role of LTx in ASLD is still debated.
View Article and Find Full Text PDFis a vaginal commensal. Cases of vaginitis, vulvovaginitis and recurrent vulvovaginitis caused by this yeast are very rare. In the oral cavity, causes stomatitis in immunocompromised patients.
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- Antibiotic resistance is a growing global issue, affecting both systemic and topical treatments for infections, highlighting the need for alternatives like antiseptics.
- Polyhexanide (PHMB) is noted for its effectiveness in controlling infections without promoting resistance, making it a viable option for treating various dermatological conditions.
- The text suggests updated clinical practices for managing wounds and skin infections, advocating for the use of innovative treatments like PHMB and Rigenase® instead of traditional topical antibiotics.
Tick Bite Alopecia: A Report of Five Cases and Review of the Literature.
Skin Appendage Disord
August 2024
Introduction: Although well-known, tick bite alopecia is rarely reported in the literature.
Case Presentations: We present five cases of alopecia of the scalp caused by tick bites. All patients were Caucasians, 2 males and 3 females, with an age ranging from 4 to 9 years (mean age: 6.
Article Synopsis
- Loxosceles rufescens is a spider that can cause bites leading to necrotic ulcers in humans; the study documents twelve cases with confirmed bites and provides detailed clinical observations.
- Seven patients developed single necrotic ulcers in various body parts, experiencing pain and burning but showing no systemic symptoms; they were treated with topical solutions and some needed antibiotics for bacterial infections.
- Recovery took up to eight weeks for all patients, but five developed scars, highlighting the need for proper identification of the spider to confirm the bite's causative agent and manage treatment effectively.
Article Synopsis
- Infection at surgical sites is common after dermatologic procedures, but using antibiotics to prevent these infections is controversial due to rising antibiotic resistance, especially in Italy where misuse is rampant.* -
- A survey distributed to dermatologists nationwide revealed that over 70% routinely use topical antibiotics post-procedure, despite growing evidence against their effectiveness in preventing infections.* -
- The results indicate a significant misunderstanding about the role of antibiotics in wound care, highlighting the urgent need for education among healthcare professionals to combat the ongoing issue of antibiotic resistance.*
Major aphthae are usually located on the dorsum of the tongue, the mucosal surface of the lips and the palate. They are large, round or oval ulcers, with a whitish-grey bed, well-defined borders and erythematous halo. They are very often accompanied by severe pain.
View Article and Find Full Text PDFBackground: Pan-enteric capsule endoscopy (PCE) provides useful information for the management of Crohn's disease (CD), especially in children. No study has evaluated the ability of PCE to characterize CD phenotypes and outcomes in children and adults.
Methods: In a prospective multicenter observational study, we recruited patients with CD >6 years from 4 centers in Italy.
Objective: Psoriasis is a chronic, inflammatory skin disease, requiring local and systemic drugs according to disease severity. This study aims to investigate the efficacy and safety of a topical treatment containing xyloglucan, pea proteins and extracts (XPO) compared to calcipotriol 50mcg/betamethasone 0.5mg ointment (CB).
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- * Ficus carica L, a plant in the Moraceae family, is identified as a cause of acute photodermatitis in five reported cases.
- * The study includes a histopathologic examination and a review of relevant literature related to these cases.
Article Synopsis
- Follicular larva migrans (FLM) is an uncommon form of hookworm-related skin infection, marked by small, round, red bumps that can develop into vesicles or pustules.* -
- These lesions typically appear on areas like the abdomen, back, buttocks, and thighs, often causing significant itching, and can show short, fragmented tracks.* -
- FLM is harder to treat with anti-helminthic medications compared to traditional cutaneous larva migrans due to the larvae's deep placement in hair follicles; the text includes two case studies and a literature review.*
Blistering skin lesions caused by stings of Hottentotta sp. scorpion.
J Eur Acad Dermatol Venereol
August 2024
Background: The role of histological inflammation at diagnosis as a possible prognostic factor for disease course has not been investigated.
Aims: To assess whether histologic findings at diagnosis could predict clinical outcomes and evaluate the association between clinical, biochemical, endoscopic, and histological findings.
Methods: Prospective single-center study including pediatric UC patients with a minimum follow-up of 12 months.
Introduction: Atopic dermatitis (AD) is a chronic disease that occurs mainly in children. Topical corticosteroids are the main treatment for mild to moderate AD, although they can induce side effects. The efficacy and tolerability of xyloglucan and pea protein (XG-PP) was compared with hydrocortisone in pediatric patients with AD as a steroid-sparing solution.
View Article and Find Full Text PDFObjective: Atopic dermatitis (AD) management requires long-term use of drugs that come with side effects. Compounds such as xyloglucan (XG) and pea proteins (PP) are emerging alternatives to corticosteroids that have shown to restore skin barrier function in preclinical studies. This double-blind, parallel, randomized, placebo-controlled clinical trial investigated the efficacy and safety of XG and PP, in adult AD patients.
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