Publications by authors named "Vera Lederer"
Neutral mesoionic carbenes (MICs) based on a 1,2,3-triazole core have had a strong impact on various branches of chemistry such as homogeneous catalysis, electrocatalysis, and photochemistry/photophysics. We present here the first general synthesis of anionic mesoionic carbenes (anMICs) based on a 1,2,3-triazole core and a borate backbone. The free anMIC is stable in solution under an inert atmosphere at low temperatures, and can be stored for several weeks.
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- - The disclosed catalyst is a zwitterionic compound that enhances efficiency in direct 1,4-additions, particularly with maleimides, achieving over 300 times higher productivity than previous methods, with total turnover numbers (TONs) reaching up to 6700.
- - This catalyst, which features acetate binding to Cu and is stabilized by a benzimidazolium counterion, has demonstrated high stereoselectivity and consistency across various Michael acceptors.
- - It can be synthesized in just four steps from N-Ph-benzimidazole with an impressive overall yield of 96%, and its robustness allows for multiple reutilizations without a significant drop in efficiency, supported by detailed mechanistic studies.