Publications by authors named "Vera Jaeggi"
Introduction: Digital trials are a promising strategy to increase the evidence base for common interventions and may convey considerable efficiency benefits in trial conduct. Although paediatric intensive care units (PICUs) are rich in routine electronic data, highly pragmatic digital trials in this field remain scarce. There are unmet evidence needs for optimal mechanical ventilation modes in paediatric intensive care.
View Article and Find Full Text PDFBackground: Intravenous arginine vasopressin is increasingly used for the treatment of critically ill children. It bears the risk of hyponatraemia with potential severe long-term sequelae, but data on hyponatraemia as a side effect of continuous vasopressin infusion for paediatric intensive care patients is scarce.
Methods: In this retrospective analysis performed at a tertiary care paediatric intensive care unit with 2000 annual admissions, patients were included if they were treated with intravenous vasopressin between 2016 and 2022.
Article Synopsis
- Antibiotic overtreatment in pediatric intensive care units (PICUs) is linked to increased multidrug resistance, leading to higher morbidity and mortality rates among patients globally.
- A retrospective study analyzed antibiotic usage in a single-center PICU from 2019 to 2021, involving 2,041 patients with a median age of 10 months, and found that antibiotic exposure was rising, averaging 59.8 days of therapy (DOT) per 100 patient days.
- The study highlighted that the highest antibiotic usage occurred in the youngest patients, those with longer stays in the ICU, specific diagnoses, and in cases resulting in death, indicating a need for better data reporting and further research to improve benchmarking efforts.