Nocturnal reflux in children and adolescents with persistent asthma and gastroesophageal reflux.

Background: A higher frequency of nocturnal gastroesophageal reflux (GER) in adult patients with respiratory symptoms has been demonstrated. The aim of this study was to determine the prevalence of nocturnal GER by using prolonged intraesophageal pH monitoring and compare it with spirometry results in children with persistent asthma.

Methods: Thirty-eight patients with persistent asthma for at least 2 years were studied.