Publications by authors named "Vera De Matos"
Background/aim: Pediatric ileocolonic Crohn disease (CD) may be difficult to distinguish from ulcerative colitis (UC) with backwash ileitis (BWI). The primary aim of the study was to determine the probability of CD in children with a confluent colitis and ileitis when newly diagnosed with inflammatory bowel disease (IBD).
Methods: A retrospective observational study of 100 newly diagnosed patients with IBD was performed.
Age-based differences in the diagnosis and management of esophageal eosinophilia.
J Allergy Clin Immunol Pract
February 2016
Background: Eosinophilic esophagitis (EoE) is hallmarked by esophageal eosinophilia, >15 eosinophils(eos)/high-powered field (hpf), unresponsive to acid inhibition, and varied symptomatology. EoE consensus guidelines do not discriminate based on age for initiating treatment.
Objective: To evaluate if age-related differences exist in managing esophageal eosinophilia and EoE within a university population.
Frequency and clinical correlations of granulomas in children with Crohn disease.
J Pediatr Gastroenterol Nutr
April 2008
Article Synopsis
- Granulomas are specifically associated with Crohn disease (CD), and a study sought to understand their frequency and importance in both untreated and treated patients, finding that 61% of untreated patients had them compared to only 24.5% of treated patients.
- The study reviewed patient records from 376 CD individuals over 7 years, highlighting the significance of biopsy sites in detecting granulomas - particularly in the upper tract and terminal ileum, which revealed 42% of cases.
- Results suggested that the presence of granulomas relates to certain clinical factors like anti-Saccharomyces cerevisiae antibodies and perianal disease but showed no link to age or other disease markers, indicating that granulomas could be crucial in diagnosing
We describe a unique series of 3 cases of biliary atresia (BA) associated with a choledochal cyst. All 3 children presented with jaundice at birth and had no other abnormalities. Although these children had a fetal form of BA, their presentation and outcome differed from those of biliary atresia splenic malformation syndrome (BASM), the well-described form of early onset BA.
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