Publications by authors named "Vera Ciornolutchii"
Introduction: Adiponectin, a key adipokine, shows promise as a non-invasive biomarker for liver cirrhosis by reflecting inflammation and metabolic changes, but conflicting findings highlight the need for a systematic review and meta-analysis to clarify its role. Our study aimed to evaluate adiponectin levels across various stages of liver cirrhosis, compare them with other chronic liver diseases (CLD) and hepatocellular carcinoma (HCC), and assess its potential as a diagnostic and prognostic biomarker.
Methods: Our systematic search was conducted on September 2023 using PubMed, EMBASE and Scopus, searching for observational studies evaluating serum and plasma adiponectin levels in liver cirrhosis.
Article Synopsis
- - Pulmonary fibrosis, particularly idiopathic pulmonary fibrosis (IPF) and secondary pulmonary fibrosis (SPF), is a progressive lung disease that requires accurate differentiation for effective treatment, which this study aims to achieve through various blood-derived ratios and hepatic scores.
- - Conducted at the "Leon Daniello" Clinical Hospital in Romania, the study included 66 patients (38 with IPF and 28 with SPF) to analyze their clinical data and assess the effectiveness of different biomarkers in distinguishing between the two types of pulmonary fibrosis using statistical methods.
- - The results showed that IPF patients had higher FIB-4 scores and RDW/PLT ratios, indicating a greater risk of liver fibrosis, while SPF patients had higher PL
Background: In instances where individuals manifest elevated transaminase levels without a clearly discernible cause, a comprehensive patient history proves invaluable in unveiling latent triggers. In this report, we present 2 cases of herb-induced liver injury (HILI) characterized by severe hypertransaminasemia attributed to the consumption of Chelidonium majus L . (also known as greater celandine [GC]), an agent considered an alternative therapeutic remedy.
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