A systematic review of endoprosthetic replacement for non-tumour indications around the knee joint.

Background: Endoprosthetic replacement (EPR) for limb salvage is an established treatment modality for orthopaedic malignancies around the knee. Increasingly, they are being used for non-tumour indications such as fractures, bone loss associated with aseptic loosening, septic loosening and ligament insufficiencies.

Methods: We reviewed the evolution and biomechanics of knee EPRs.