Publications by authors named "Vennila Gopal"
The epidemiology of different respiratory viral infections is believed to be affected by prior viral infections in addition to seasonal effects. This PROSPERO-registered systematic review identified 7388 studies, of which six met our criteria to answer the question specifically. The purpose of this review was to compare the prevalence of sequential viral infections in those with previously documented positive versus negative swabs.
View Article and Find Full Text PDFThe PI3K/AKT signaling pathway plays essential roles in multiple cellular processes, which include cell growth, survival, metabolism, and motility. In response to internal and external stimuli, the PI3K/AKT signaling pathway co-opts other signaling pathways, cellular components, and cytoskeletal proteins to reshape individual cells. The cytoskeletal network comprises three main components, which are namely the microfilaments, microtubules, and intermediate filaments.
View Article and Find Full Text PDFArticle Synopsis
- The epithelial to mesenchymal transition (EMT) is a key process in cancer metastasis where epithelial cells transform into motile mesenchymal cells, involving significant changes in cell shape and behavior.
- The cytoskeleton, made up of actin filaments, microtubules, and intermediate filaments, is crucial for this transformation, as it regulates cell structure and movement during EMT.
- Targeting the components of the cytoskeleton may offer new strategies for cancer therapy, particularly in combating multidrug-resistant cancer cells.