A critical process variable-regulated, parameter-balancing auxostat, performed using disposed COVID-19 personal protective equipment-based substrate mixture, yields sustained and improved endoglucanase titers.

Fifty percent of the overall operational expenses of biorefineries are incurred during enzymatic-saccharification processes. Cellulases have a global-market value of $1621 USD. Dearth of conventional lignocelluloses have led to the exploration of their waste stream-based, unconventional sources.

2,4-Di-Tert-Butylphenol Isolated From an Endophytic Fungus, , Reduces Virulence and Quorum Sensing in .

is among the top three gram-negative bacteria according to the WHO's critical priority list of pathogens against which newer antibiotics are urgently needed and considered a global threat due to multiple drug resistance. This situation demands unconventional antimicrobial strategies such as the inhibition of quorum sensing to alleviate the manifestation of classical resistance mechanisms. Here, we report that 2,4-di-tert-butylphenol (2,4-DBP), isolated from an endophytic fungus, , inhibits the quorum-sensing properties of We have found that treating with 2,4-DBP substantially reduced the secretion of virulence factors as well as biofilm, and its associated factors that are controlled by quorum sensing, in a dose-dependent manner.