Background: Thin Film Transistors (TFTs) are increasingly prevalent electrical components in display products, ranging from smartphones to diagonal flat panel TVs. The limitations in existing TFT technologies, such as high-temperature processing, carrier mobility, lower ON/OFF ratio, device mobility, and thermal stability, result in the search for new semiconductor materials with superior properties.
Objective: The main objective of this present work is to fabrícate the efficient Single-Walled Carbon Nanotube Thin Film Transistor (TFT) for flat panel display.
Background: We developed the FORCE platform to overcome limitations of oligonucleotide delivery to muscle and enable their applicability to neuromuscular disorders. The platform consists of an antigen-binding fragment, highly specific for the human transferrin receptor 1 (TfR1), conjugated to an oligonucleotide via a cleavable valine-citrulline linker. Myotonic dystrophy type 1 (DM1) is a neuromuscular disorder caused by expanded CUG triplets in the DMPK RNA, which sequester splicing proteins in the nucleus, lead to spliceopathy, and drive disease progression.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
The aim of this work was to study the characteristics of composites fabricated from cellulose (CL) and chitosan (CS) blends that were reinforced with different tannic acid (TA) and gallic acid (GA) concentrations. The structure and antibacterial activity of CL/CS composite films were investigated with the addition of TA and GA. The composite films were subjected to mechanical, water contact angle (WCA), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM), and antibacterial activity tests.
View Article and Find Full Text PDFIn the present study, we demonstrated a cost-effective chia seed-based triboelectric nanogenerator (C-TENG), leveraging the triboelectric properties of chia seeds. The C-TENGs are fabricated with a simple architecture, establishing adaptability, cost effectiveness, and versatility as an ecofriendly harvester of mechanical energy. The C-TENG exhibits open- circuit voltage and short-circuit currents on the order of 501.
View Article and Find Full Text PDFA reflective dual-band linear-to-circular polarizer for C and X-band application is presented. The proposed elliptical Frequency Selective Surface (FSS) is capable of enhancing the polarization control and minimizes the cross-polarization compared to traditional circular or square geometries. The linear-to-circular polarization is achieved through two elliptical apertures, where each shape generates orthogonal modes with a 90° phase shift.
View Article and Find Full Text PDFNanoparticles derived from biological sources are currently garnering significant interest due to their diverse range of potential applications. The purpose of the study was to synthesize Al-doped nanoparticles of zinc oxide (ZnO) from leaf extracts of and assess their antioxidant and antimicrobial activity using some bacterial and fungal strains. These nanoparticles were analyzed using X-ray diffraction (XRD), ultraviolet-visible (UV-vis) spectroscopy, Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM) with energy dispersive X-ray analysis (EDAX), transmission electron microscopy (TEM), and thermogravimetric analysis/differential thermal analysis (TG-DTA).
View Article and Find Full Text PDFBackground and aim Oral health is an integral part of overall general health. Understanding the variables that affect the use of dental services can help overcome the challenges and lessen disparities in oral health. There are no significant reliable questionnaires available for determining factors that influence dental care utilization.
View Article and Find Full Text PDFThis research aims to use energy harvested from conductive materials to power microelectronic components. The proposed method involves using vibration-based energy harvesting to increase the natural vibration frequency, reduce the need for battery replacement, and minimise chemical waste. Piezoelectric transduction, known for its high-power density and ease of application, has garnered significant attention.
View Article and Find Full Text PDFThe synthesis of Al-ZnO nanoparticles (NPs) was achieved using a green synthesis approach, utilizing leaf extract from (L.) in a straightforward co-precipitation method. The goal of this study was to investigate the production of Al-ZnO nanoparticles through the reduction and capping method utilizing (L.
View Article and Find Full Text PDFThe implementation of hard-facing alloy on the existing materials caters the need for high-performance surfaces in terms of wear and high temperatures. The present research explore the effect of Plasma Transferred Arc Welding (PTAW) parameters and powder composition on dilution, microstructure and hardness of the commonly used hard-facing alloy Ni-Cr-Si-B powder. The hard-facing alloy was deposited with three weight proportions of boron (2.
View Article and Find Full Text PDFAnodized aluminum oxide (AAO) molds were used for the production of large-area and inexpensive superhydrophobic polymer films. A controlled anodization methodology was developed for the fabrication of hierarchical micro-nanoporous (HMN) AAO imprint molds (HMN-AAO), where phosphoric acid was used as both an electrolyte and a widening agent. Heat generated upon repetitive high-voltage (195 V) anodization steps is effectively dissipated by establishing a cooling channel.
View Article and Find Full Text PDFTitanium dioxide (TiO) is a common pigment used in food packaging to provide a transparent appearance to plastic packaging materials. In the present study, poly(butylene adipate-co-terephthalate) (PBAT) incorporated with lignin-TiO nanoparticles (L-TiO) eco-friendly composite films was prepared by employing an inexpensive melting and hot-pressing technique. The P-L-TiO composite films have been studied using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscope (SEM), Thermogravimetric analysis (TGA), and Differential scanning calorimetry (DSC) analysis.
View Article and Find Full Text PDFThe pervasive application of chemical pesticides is globally recognised for its effectiveness and cost-efficiency in controlling pest populations. However, this approach has inadvertently impacted a diverse array of organisms, including humans and beneficial insects, notably those that naturally regulate pest populations. This review synthesises current research on both the direct and indirect effects of pesticides on parasitoid wasps.
View Article and Find Full Text PDFThe Mycobacterium tuberculosis trifunctional enzyme (MtTFE) is an αβ tetrameric enzyme in which the α-chain harbors the 2E-enoyl-CoA hydratase (ECH) and 3S-hydroxyacyl-CoA dehydrogenase (HAD) active sites, and the β-chain provides the 3-ketoacyl-CoA thiolase (KAT) active site. Linear, medium-chain and long-chain 2E-enoyl-CoA molecules are the preferred substrates of MtTFE. Previous crystallographic binding and modeling studies identified binding sites for the acyl-CoA substrates at the three active sites, as well as the NAD binding pocket at the HAD active site.
View Article and Find Full Text PDFLocust bean gum (LBG), a polysaccharide-based natural polymer, is being widely researched as an appropriate additive for various products, including food, gluten-free formulations, medicines, paper, textiles, oil well drilling, cosmetics, and medical uses. Drug delivery vehicles, packaging, batteries, and catalytic supports are all popular applications for biopolymer-based materials. This review discusses sustainable food packaging and drug delivery applications for LBG.
View Article and Find Full Text PDFAtrazine (ATZ, CHClN) is a widely used synthetic herbicide that contaminates drinking water. It is a known endocrine disruptor that disrupts various molecular pathways involved in hormone signaling, and DNA damage, and can cause reproductive disorders, including decreased fertility, and abnormal development of reproductive organs, as revealed in animal model studies. However, the effect of ATZ on steroidogenesis in the male reproductive system, especially reduction of ketosteroids to hydroxysteroids, remains unclear.
View Article and Find Full Text PDFThis paper proposes a convolutional neural network (CNN) model of the signal distribution control algorithm (SDCA) to maximize the dynamic vehicular traffic signal flow for each junction phase. The aim of the proposed algorithm is to determine the reward value and new state. It deconstructs the routing components of the current multi-directional queuing system (MDQS) architecture to identify optimal policies for every traffic scenario.
View Article and Find Full Text PDFThe development of new drugs derived from plant sources is of significant interest in modern pharmacy. One of the promising plant sources for introduction into pharmaceuticals is (L.) Sch.
View Article and Find Full Text PDFEphrin-B-EphB signaling can promote pain through ligand-receptor interactions between peripheral cells, like immune cells expressing ephrin-Bs, and EphB receptors expressed by DRG neurons. Previous studies have shown increased ephrin-B2 expression in peripheral tissues like synovium of rheumatoid and osteoarthritis patients, indicating the clinical significance of this signaling. The primary goal of this study was to understand how ephrin-B2 acts on mouse and human DRG neurons, which express EphB receptors, to promote pain and nociceptor plasticity.
View Article and Find Full Text PDFIn this research work, a coated paper was prepared with poly (butylene adipate-co-terephthalate) (PBAT) film to explore its use in eco-friendly food packaging. The paper was coated with PBAT film for packaging using hot pressing, a production method currently employed in the packaging industry. The coated papers were evaluated for their structural, mechanical, thermal, and barrier properties.
View Article and Find Full Text PDFThe green synthesis of zinc oxide nanoparticles (ZnO NPs) using plants has grown in significance in recent years. ZnO NPs were synthesized in this work via a chemical precipitation method with (JS) leaf extract serving as a capping agent. These NPs were characterized using UV-vis spectroscopy, FT-IR, XRD, SEM, TEM, TGA, and DTA.
View Article and Find Full Text PDFBiobased plastics provide a sustainable alternative to conventional food packaging materials, thereby reducing the environmental impact. The present study investigated the effectiveness of chitosan with varying levels of Moringa oleifera seed powder (MOSP) and tannic acid (TA). Chitosan (CS) biocomposite films with tannic acid acted as a cross-linker, and Moringa oleifera seed powder served as reinforcement.
View Article and Find Full Text PDF, a gram-positive bacterium found in soil and water, rarely causes infections in immunocompetent patients. Diagnosing and treating nocardiosis can be challenging due to its infrequency and the similarity of its symptoms to other diseases. We describe the case of a middle-aged male with a history of latent tuberculosis who presented with hemoptysis.
View Article and Find Full Text PDFBackground: Enteric fever caused by Salmonella enterica Typhi and Salmonella Paratyphi A is an important public health problem, especially in low-income and middle-income countries with limited access to safe water and sanitation. We present results from, to our knowledge, the first ever human study of a bivalent paratyphoid A-typhoid conjugate vaccine (Sii-PTCV).
Methods: In this double-blind phase 1 study, 60 healthy Indian adults were randomly assigned (1:1) to receive a single intramuscular dose of either Sii-PTCV or typhoid conjugate vaccine (Typbar-TCV).