Publications by authors named "Venkataramana S"

Magnesium is renowned for its favorable low-density attributes, rendering it a viable choice for commercial engineering applications in which weight has substantial design implications. Magnesium (Mg) stands as a readily obtainable metallic element, exhibiting robustness, efficient heat dissipation, and excellent damping properties. The utilization of pure magnesium remains infrequent due to its susceptibility to instability under high temperatures and pronounced vulnerability to corrosion within humid environments.

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Background: Delayed gastric emptying play an important role in the pathology of functional dyspepsia. Owing to their functional attributes in alleviating the gastrointestinal disorders, single or polyherbal formulations have gained attention to treat the symptoms of functional dyspepsia. We have investigated the safety and efficacy of a novel formulation of Ferula asafoetida oleo resin and standardized Silybum marianum extract (Asdamarin).

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Article Synopsis
  • Intestinal inflammation leads to neurotoxicity in the enteric nervous system (ENS) due to immune cell activation and iNOS-derived nitric oxide (NO).
  • The accumulation of neutrophils and macrophages in the intestinal wall occurs shortly after inflammation begins, which correlates with neuronal damage and increased iNOS expression.
  • Inhibition of iNOS successfully prevents neuron loss and may protect against associated smooth muscle hyperplasia, highlighting a critical pathway for immune-induced damage to ENS during intestinal inflammation.
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Calcineurin inhibitor induced thrombotic microangiopathy is a rare but well recognized complication of a renal transplantation that occurs in 1% of the patients who are on tacrolimus immunosuppression. Among the other aetiological factors of the "de-novo" Thrombotic Microangiopathy (TMA), the condition especially has to be differentiated from an antibody mediated rejection, as both have different pathogenesis, therapeutic connotations and outcomes.We report a case of a middle aged female renal transplant recipient treated with tacrolimus, who developed localised thrombotic microangiopathy in the early post transplantation period.

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Article Synopsis
  • Hyperplasia of intestinal smooth muscle cells (ISMC) occurs during inflammation and may be regulated by nitric oxide (NO) from enteric neurons, specifically through neuronal NO synthase (nNOS).
  • Chemical NO donors were found to inhibit growth of ISMC, while the use of inhibitors and stimulators showed that the growth regulation primarily relies on a cGMP-dependent mechanism, with some involvement of cAMP.
  • In a colitis model, a reduction in nNOS axons was observed before the onset of ISMC hyperplasia, suggesting that decreased nNOS expression could contribute to this excessive growth during inflammation.
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Sorption capacity of different parts of Eichhornia crassipes, such as rhizome, root, lamina and petiole on basic aurophine-o was studied in a batch system. The equilibrium uptake capacity was observed as 13.65 mg/g (using root), 13.

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An assessment of tolerance to water stress based upon measurements of cellular membrane thermostability and in vivo nitrate reductase activity (NRA) was made using young leaves of sugar-cane (Saccharum officinarum L. commercial hybrids, Co 419, Co 740 and Co 1148) subjected to stress (51 to 61 d old) and subsequent hydration. An average reduction in leaf water potential (Ψ ) from -0.

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