An Approach for Live Motion Correction for TRUS-MR Prostate Fusion Biopsy using Deep Learning.

TRUS-MR fusion guided biopsy highly depends on the quality of alignment between pre-operative Magnetic Resonance (MR) image and live trans-rectal ultrasound (TRUS) image during biopsy. Lot of factors influence the alignment of prostate during the biopsy like rigid motion due to patient movement and deformation of the prostate due to probe pressure. For MR-TRUS alignment during live procedure, the efficiency of the algorithm and accuracy plays an important role.

Short communication: Y chromosome microchimerism in female peripheral blood.

Male DNA of recognized fetal origin can be detected in the maternal circulation many years after delivery. It is referred to as fetal microchimerism, and is thus a possible explanation for the existence of low-level Y chromosome mosaicisms. Employing the nested polymerase chain reaction (PCR) technique, Y-specific markers were investigated in 13 cases with abnormal sex chromosome and 31 normal women.

Association between novel HLA-G genotypes and risk of recurrent miscarriages: a case-control study in a South Indian population.

HLA-G is a nonclassical histocompatibility complex member associated with fetal tolerance of the mother observed during pregnancy. Despite its being a less polymorphic gene, a number of studies have evaluated the role of HLA-G gene polymorphisms on the risk of pregnancy-related complications. A 14-bp deletion polymorphism in exon 8 (3'UTR) was known to influence the levels of soluble HLA-G, differential splicing of the transcript, and also the induction of interleukin-10 secretion.

Recurrent early pregnancy loss and endothelial nitric oxide synthase gene polymorphisms.

Objective(s): Studies on the relation between endothelial nitric oxide synthase (eNOS) activity in implantation and maintenance of pregnancy highlights the importance of eNOS gene polymorphisms in recurrent early pregnancy loss (REPL). We investigated the relationship between idiopathic REPL and polymorphisms in eNOS among South Indian women.

Methods: A case-control study comprising 145 females with REPL and 99 control females.

Association of CYP1A1 gene polymorphism with recurrent pregnancy loss in the South Indian population.

Background: We investigated the relationship between idiopathic recurrent pregnancy loss (RPL) and genetic polymorphisms in phase I and phase II detoxification genes which include CYP1A1, CYP2D6, GSTM1, GSTP1 and GSTT1.

Method: A case-control study comprised 160 females with RPL and 63 healthy controls with a successful reproductive history.

Results: The CYP1A1 variant allele was present at frequencies of 0.