Effect of micro osteo-perforations (MOP) on the rate of tooth movement and levels of interleukin- 1β - a split mouth study.

Introduction: Various procedures are available today to enhance tooth movement, with relative success rates, one among them being micro osteo-perforation (MOP). Our aim is to assess the rate of tooth movement and interleukin-1β levels in gingival crevicular fluid levels (GCF) after MOPs.

Methods: A group of 22 patients were selected, who required first premolars extraction and were designated for the split mouth study with equal allocation.

Dermatoglyphics as a Novel Method for Assessing Intelligence Quotient in Children Aged 5-11 Years: A Cross-sectional Study.

Aim: To measure the IQ and record dermatoglyphic patterns of children including intellectually disabled aged between 5 years and 11 years and to correlate them.

Materials And Methods: The present study was a cross-sectional study conducted in two private schools in the city corporation limits. A total of 300 children aged between 5 years and 11 years were equally allocated into three groups based on IQ using covariate adaptive randomization.

Evaluation of Mechanical and Physical Properties of Clinically Used and Recycled Superelastic NiTi Wires.

Introduction: The initial leveling and aligning phase has been simplified with the introduction of superelastic nickel-titanium archwires. The relatively high cost of these wires has prompted some of the clinicians to reuse them after sterilization. The quantitative changes in the surface properties of superelastic 'NiTi' wires after clinical application and recycling by autoclave method have not been established in earlier studies.

Stimulus intensity in left ventricular leads and response to cardiac resynchronization therapy.

Background: Increased left ventricular (LV) stimulus intensity has been shown to improve conduction velocity and cardiac output. However, high-output pacing would shorten device battery life. Our prospective trial analyzed the clinical effects of high- versus low-output LV pacing.

Coronary artery disease potentiates response to dofetilide for rhythm control of atrial fibrillation.

Background: Dofetilide, a class III antiarrhythmic, is one of the few alternatives to amiodarone in patients with atrial fibrillation (AF) and heart failure or coronary artery disease (CAD). While amiodarone has been extensively studied, little is known about predictors of response to dofetilide. We sought to identify clinical parameters associated with dofetilide success in a large cohort of patients with AF.

The relationship of bipolar left ventricular pacing stimulus intensity to cardiac depolarization and repolarization in humans with cardiac resynchronization devices.

Background: Myocardial depolarization can be altered by varying pacing stimulus output. This may have implications on response rates for cardiac resynchronization therapy (CRT). The purpose of our study was to determine the relationship of left ventricular (LV) pacing stimulus intensity to measures of depolarization and repolarization in humans with CRT devices.

Effect of comprehensive therapeutic lifestyle changes on prehypertension.

Although national clinical guidelines promulgate therapeutic lifestyle changes (TLC) as a cornerstone in the management of prehypertension, there is a perceived ineffectiveness of TLC in the real world. In this study of 2,478 ethnically diverse (African Americans n = 448, Caucasians n = 1,881) men (n = 666) and women (n = 1,812) with prehypertension and no known atherosclerotic cardiovascular disease, diabetes mellitus, or chronic kidney disease, we evaluated the clinical effectiveness of TLC in normalizing blood pressure (BP) without antihypertensive medications. Subjects were evaluated at baseline and after an average of 6 months of participation in a community-based program of TLC.

Utility of three-dimensional echocardiography in percutaneous closure of paravalvular leak.

The images and videos presented in this case report demonstrate the utility of live three-dimensional (3D) transoesophageal echocardiography (TEE) in guiding the percutaneous closure of paravalvular leak (PVL). This method provides high-quality real time assistance for transseptal puncture and deployment of the closure device through the PVL.

Prehypertension: detection, evaluation, and management.

Prehypertension was defined as a discrete category in 1993. There is evidence to support active management of this entity given the increased risk of hypertension, cardiovascular disease, heart failure, and stroke. There have been few comprehensive summaries on the management of this population.