Evaluation of enamel remineralizing potential of self-assembling peptide P-4 on artificially induced enamel lesions in vitro.

Purpose: The purpose of this study was to evaluate the remineralizing efficacy of self-assembling peptide (SAP) P-4 qualitatively and quantitatively using scanning electron microscopy (SEM) and energy-dispersive X-ray (EDX), respectively.

Methodology: Enamel samples (n = 24) were prepared by sectioning extracted premolars and subjected for demineralization to create artificial enamel lesions. The structural and elemental concentrations (calcium and phosphate weight %) were assessed to obtain baseline data using SEM and EDX spectroscopy, respectively.