Podocalyxin in the onset of nephropathy among Indian type 2 diabetes mellitus patients.

The diabetic nephropathy is one of the most prevalent microvascular complications with type 2 diabetes mellitus. The most accurate and widely used marker for diabetic nephropathy is microalbuminuria and it is also regarded as conventional method. However, it is not a sensitive or specific nephropathy biomarker.

Interleukin-6 and uric acid among type 2 diabetes mellitus patients with coronary artery disease.

The type 2 diabetes mellitus is considering as metabolic disorder, the unfavourable long-term outcomes and closely associated with chronic inflammation. The present study investigated to explore the association of interleukin-6 and uric acid in patients with type 2 diabetes mellitus and coronary artery disease. Newly diagnosed CAD patients with T2DM (100) and T2DM and CAD patients after 5 years (100) underwent detailed anthropometric, demographic, biochemical and experimental characterization.

Association of obesity and insulin resistance to gestational diabetes mellitus.

Gestational diabetes mellitus is most commonly observed in pregnant women and it was significantly linked with dyslipidemia, obesity and insulin resistance. The present study aimed to evaluate the association of obesity, insulin resistance risk of gestational diabetes mellitus. This cross sectional study included total ninety (90) subjects out of this 30 subjects with 1st trimester, another 30 subjects were considered 2nd trimester and remaining 30 were 3rd trimester.

Serum adiponectin in Indian women with polycystic ovary syndrome.

Poly Cystic Ovary Syndrome (PCOS) is mainly characterised by reproductive hormonal imbalance and increased androgen levels, ovulatory dysfunction and polycystic appearing ovaries on ultrasonography. The obesity is common factor to cause PCOS and this adipocytokines play an important role to cause obesity related disorders. Hence, the present study aimed to evaluate the role of adiponectin in women with PCOS compared them with healthy controls.

Association of interleukin 6 and uric acid levels in patients with type 2 diabetes mellitus.

Type 2 Diabetes Mellitus (T2DM) patients with coronary artery disease (CAD) coupled with hypertension (HTN) are leading cause of morbidity and mortality. Association of Interleukin 6 and uric acid levels can be used for early detection of CAD in patients with T2DM. This cross sectional study included 120 study participants, were sub grouped into three Group 1: controls (n=30), Group 2: CAD, HTN without T2DM (n=30) and Group 3: CAD, HTN with T2DM (n=30).

Urinary nephrin linked nephropathy in type-2 diabetes mellitus.

Diabetic nephropathy is a one of the risk factor for end stage renal disease in patients with type 2 diabetes mellitus. Urinary micr oalbumin currently marker using for diagnosis of nephropathy in type 2 diabetes mellitus due to its larger variability and less specificity. Urinary nephrin is podocyte protein can be act as a early predictable and prognostic marker than micro albumin for nephropathy in type 2 diabetes mellitus.

Linking adiponectin expression and kidney dysfunction among Indian patients with and without diabetic nephropathy.

Diabetic kidney disease is a common cause of end stage renal disease has a high incidence rate in population with type 2 diabetes mellitus patients. Adiponectin is an adipocytokine shown to strive anti-diabetic, anti-oxidative as well as anti-inflammatory. The present study aimed to determine the serum adiponectin levels in type 2 diabetes mellitus and explore its association with nephropathy.

Association of adiponectin levels with polycystic ovary syndrome among Indian women.

Polycystic Ovary Syndrome (PCOS) is a hormonal condition where women reproductive hormones are out of endocrinal balance. Women with PCOS frequently exhibit obesity, which causes irregularities in the levels of adipocytes like adiponectin. It is hypothesized that the altered adiponectin levels also play a role in the endocrine and metabolic abnormalities seen in PCOS women.

Urinary Nephrin is a Sensitive Marker to Predict Early Onset of Nephropathy in Type 2 Diabetes Mellitus.

 The present study has been designed to evaluate urinary nephrin that best predicts the occurrence of renal dysfunction in type 2 diabetes mellitus patients and its correlation with clinical parameters of nephropathy.  A total of 80 type 2 diabetes mellitus and 40 age- and gender-matched healthy controls were recruited. Biochemical and clinical parameters were analyzed in all the study participants.

Adiponectin Can Be an Early Predictable Marker for Type 2 Diabetes Mellitus and Nephropathy.

Background Several studies have examined serum adiponectin concentrations in prediabetes, newly diagnosed type 2 diabetes mellitus (T2DM), and other types of diabetes associated with the risk of T2DM and diabetic nephropathy (DN); however, the results to date are inconclusive. An aim of the current study is to determine whether adiponectin is a useful marker for the earlier development of T2DM and DN. Methodology This cross-sectional study included 400 subjects.