Atypical Acetylcholine Receptors on the Neurons of the Turkish Snail.

Using electrophysiology, the effect of nicotinic acetylcholine receptor (nAChR) ligands on acetylcholine-induced depolarization in the neurons of Helix lucorum snail was studied. It was found that the α-conotoxin PnIA [R9, L10], a selective antagonist of α7 nAChR, and α-cobratoxin (antagonist of α7 and muscle-type nAChR) suppressed neuronal depolarization. Fluorescence microscopy showed staining of the neurons with fluorescently labeled α-bungarotoxin; this staining was reduced by pretreatment with α-cobratoxin.

The Oxidation-Induced Autofluorescence Hypothesis: Red Edge Excitation and Implications for Metabolic Imaging.

Endogenous autofluorescence of biological tissues is an important source of information for biomedical diagnostics. Despite the molecular complexity of biological tissues, the list of commonly known fluorophores is strictly limited. Still, the question of molecular sources of the red and near-infrared excited autofluorescence remains open.

[Applicability of antibacterial agents in chronic tonsillitis treatment].

The purpose of the present study was to evaluate the effectiveness of nitrofuranes applied for the treatment of chronic tonsillitis. A total of 92 subjects divided into three cohorts were involved in this study. Cohort 1 included 43 patients presenting with decompensated chronic tonsillitis and having pathogens in palatine tonsil lacunae.

[STIMULATION OF HaCaT KERATINOCYTES AND RATS MESENCHYMAL STROMAL CELLS PROLIFERATION BY FEMTOSECOND LASER PULSES].

The influence of femtosecond laser pulses on the proliferative activity of HaCaT keratinocytes and mesenchymal stromal cells (MSC) rats was studied. The growth media was exposed by laser pulses with wavelength 590 nm and duration 30 fs. The dependence of proliferative activity of cells on the dose was showed in the range 6-4299 J/cm2.

The last frontier: catch records of white sharks (Carcharodon carcharias) in the Northwest Pacific Ocean.

White sharks are highly migratory apex predators, globally distributed in temperate, sub-tropical, and tropical waters. Knowledge of white shark biology and ecology has increased recently based on research at known aggregation sites in the Indian, Atlantic, and Northeast Pacific Oceans; however, few data are available for the Northwest Pacific Ocean. This study provides a meta-analysis of 240 observations of white sharks from the Northwest Pacific Ocean between 1951 and 2012.

[Experience with fenspiride in a rhinosurgeon's practice].

The postoperative use of fenspiride in patients undergoing various surgical interventions into the nasal cavity is shown to substantially change the course of posttraumatic rhinitis. With this therapy, fibrinous fur disappeared 2 days earlier than when conventional treatment was performed, and mucosal moisture restored 2.3 times more rapidly than that in those treated without using fenspiride.