Evaluation of Antioxidant and Antimicrobial Properties of Murtilla Leaves (.) in Beef Patties: Effects on Quality Parameters and Shelf Life.

Beef patties are highly consumed worldwide. However, its formulations often include synthetic antioxidants and antimicrobials. Murtilla (.

Molecular Characteristics and Processing Technologies of Dairy Products from Non-Traditional Species.

Non-bovine dairy animals, commonly referred to as non-traditional dairy species, include goats, sheep, yaks, buffalo, donkeys, alpacas, llamas, and other less commonly farmed species. These animals have been integral to livestock systems since ancient times, providing milk and other essential products. Despite their historical significance, dairy production from many of these species remains predominantly confined to rural areas in developing countries, where scientific advancements and technical improvements are often limited.

T cell epitope mapping reveals immunodominance of evolutionarily conserved regions within SARS-CoV-2 proteome.

As SARS-CoV-2 variants continue to emerge capable of evading neutralizing antibodies, it has become increasingly important to fully understand the breadth and functional profile of T cell responses to determine their impact on the immune surveillance of variant strains. Here, sampling healthy individuals, we profiled the kinetics and polyfunctionality of T cell immunity elicited by mRNA vaccination. Modeling of anti-spike T cell responses against ancestral and variant strains of SARS-CoV-2 suggested that epitope immunodominance and cross-reactivity are major predictive determinants of T cell immunity.

Impact of Novel Foods on the Human Gut Microbiome: Current Status.

The microbiome is a complex ecosystem of microorganisms that inhabit a specific environment. It plays a significant role in human health, from food digestion to immune system strengthening. The "Novel Foods" refer to foods or ingredients that have not been consumed by humans in the European Union before 1997.

Environmental impacts of medium-scale pig farming at technical and economic optimum production weight in Mexico.

Medium-scale pig production systems, which make up 30 % of Mexico's pig farms, face two key obstacles impacting their economic and financial performance. The first is the absence of a sales plan based on pigs' weight, which negatively affects both profitability and resource management. The second obstacle is inadequate waste management, which hampers efforts to mitigate environmental impacts generated by pig farms.

Natural Killer Cell Dysfunction In Human Bladder Cancer Is Caused By Tissue-Specific Suppression of SLAMF6 Signaling.

NK cells are innate lymphocytes critical for surveillance of viruses and tumors, however the mechanisms underlying NK cell dysfunction in cancer are incompletely understood. We assessed the effector function of NK cells from bladder cancer patients and found severe dysfunction in NK cells derived from tumors versus peripheral blood. While both peripheral and tumor-infiltrating NK cells exhibited conserved patterns of inhibitory receptor over-expression, this did not explain the observed defects in NK surveillance in bladder tumors.

Changes in wider field swept-source OCT angiography vascular metrics with anti-vascular endothelial growth factor therapy in central retinal vein occlusion.

Purpose: To investigate the impact of anti-VEGF therapy on vascular metrics in eyes with macular edema secondary to central retinal vein occlusion (CRVO) using wider field swept-source OCT angiography (WF SS-OCTA).

Methods: We included 23 eyes with macular edema associated with non-ischemic CRVO from 22 patients treated with anti-VEGF therapy (median number of injections: 5 [2-9]). Changes in vessel density (VD), vessel skeletonized density (VSD), and foveal avascular zone (FAZ) parameters were measured using WF SS-OCTA.

Seven Epidemic Waves of COVID-19 in a Hospital in Madrid: Analysis of Severity and Associated Factors.

(1) Background: COVID-19 has evolved during seven epidemic waves in Spain. Our objective was to describe changes in mortality and severity in our hospitalized patients. (2) Method: This study employed a descriptive, retrospective approach for COVID-19 patients admitted to the Hospital de Fuenlabrada (Madrid, Spain) until 31 December 2022.

Review: Effect of Experimental Diets on the Microbiome of Productive Animals.

The microorganisms that inhabit the gastrointestinal tract are responsible for multiple chains of reactions that affect their environment and modify the internal metabolism, their study receives the name of microbiome, which has become more relevant in recent years. In the near future, the challenges related to feeding are anticipated to escalate, encompassing the nutritional needs to sustain an overpopulated world. Therefore, it is expected that a better understanding of the interactions between microorganisms within the digestive tract will allow their modulation in order to provide an improvement in the immune system, feed efficiency or the promotion of nutritional characteristics in production animals, among others.

[Quantitative evaluation of a SEIR model for forecasting COVID-19 cases].

Introduction: Epidemiological models have been widely used during the COVID-19 pandemic, although performance evaluation has been limited. The objective of this work was to thoroughly evaluate a SEIR model used for the short-term (1 to 3 weeks) prediction of cases, quantifying its actual past performance, and its potential performance by optimizing the model parameters.

Methods: Daily case forecasts were obtained for the first wave of cases (July 31, 2020 to March 11, 2021) in the district of General Pueyrredón (Argentina), quantifying the model performance in terms of uncertainty, inaccuracy and imprecision.

Open Science Drone Toolkit: Open source hardware and software for aerial data capture.

Despite the increased access to scientific publications and data as a result of open science initiatives, access to scientific tools remains limited. Uncrewed aerial vehicles (UAVs, or drones) can be a powerful tool for research in disciplines such as agriculture and environmental sciences, but their use in research is currently dominated by proprietary, closed source tools. The objective of this work was to collect, curate, organize and test a set of open source tools for aerial data capture for research purposes.

Langevin equation for the collective motions of a binary astrophysical system.

According to Thirring's condition, the thermodynamic equilibrium is not possible between two systems with negative heat capacities. Since the existence of negative heat capacity is a rule rather an exception in astrophysics, we would like to analyze the possibility of the thermodynamic equilibrium for a paradigmatic astrophysical situation: the binary system. The possible explanation arises after decomposing the dynamical variables into internal and collective degrees of freedom, which enables us to reinterpret binary systems as two systems A and B that interact between them through a third low dimensional system C.

Regulation of DC metabolism by nitric oxide in murine GM-CSF cultures.

The CD11c MHCII compartment within GM-CSF cultures consists of a MHCII CD11b population (GM-Macs) and a MHCII CD11b population (GM-DCs), with different metabolic profiles. GM-Macs upregulate iNOS and produce nitric oxide (NO) upon TLR activation inhibiting mitochondrial respiration (OXPHOS) while promoting glycolytic metabolism in GM-DCs, which naturally do not express iNOS.

Quantitative methods to determine the student workload. I. Empirical study based on digital platforms.

We present a quantitative study of an online course developed during COVID19 sanitary emergency in Chile. We reconstruct the teaching-learning process considering the activity logs on digital platforms in order to answer the question of How do our students study? The results from the analysis evidence the complex adaptive character of the academic environment, which exhibits regularities similar to those found in financial markets (e.g.

Quantitative methods to determine the student workload: II. Statistical models for the microcurricular performance indicators.

Previously, we observed that the student workload follows an inverse relation with the learning rate (an application of the kinematic notion of speed contextualized to the learning process). Motivated by this finding, we propose a quantitative estimation of the learning rate using a different source of information: the historical records of final grades of a given course. According to empirical data analyzed in other similar studies, the distribution functions of final grades exhibit a regular pattern: a Gaussian behavior for the approval region and a homogeneous distribution for the failed one.

Maqui (): A Natural Antioxidant to Improve Quality of Meat Patties.

Aristotelia chilensis is an endemic shrub of the South Pacific with high concentrations of bioactive compounds in its leaves and, therefore, it is highly valued. The effect of Aristotelia chilensis leaf powders (maqui leaf powders; Ma) on the quality and shelf life of beef patties during 7 days of storage was investigated. Five beef patties treatments were prepared: (1) Control without antioxidants (CT); (2) Beef patties with synthetic antioxidants plus color (250 mg/kg) (PL); (3) Beef patties with 500 ppm of maqui leaf powders (Ma500); (4) Beef patties with 1000 ppm of maqui leaf powders (Ma1000); and (5) Beef patties with 2000 ppm of maqui leaf powders (Ma2000).

Analysis of Muscle Lipidome in Juvenile Rainbow Trout Fed Rapeseed Oil and Cochayuyo Meal.

This study aimed to analyze the effects on the lipidome of juvenile muscle fed 90% "rapeseed" oil and different amounts of "Cochayuyo" meal (1.5, 3 and 6%) as a replacement for cellulose. The analysis allowed for the identification of 329 lipids, mainly represented by phospholipids and fatty esters.

Quantum Walks: Schur Functions Meet Symmetry Protected Topological Phases.

This paper uncovers and exploits a link between a central object in harmonic analysis, the so-called Schur functions, and the very hot topic of symmetry protected topological phases of quantum matter. This connection is found in the setting of quantum walks, i.e.

Natural Antioxidants from Endemic Leaves in the Elaboration of Processed Meat Products: Current Status.

During the last few years, consumers' demand for animal protein and healthier meat products has increased considerably. This has motivated researchers of the meat industry to create products that present healthier components while maintaining their safety, sensory characteristics, and shelf life. Concerning this, natural plant extracts have gained prominence because they can act as antioxidants and antimicrobials, increasing the stability and shelf life of processed meat products.

Rac inhibition as a novel therapeutic strategy for EGFR/HER2 targeted therapy resistant breast cancer.

Background: Even though targeted therapies are available for cancers expressing oncogenic epidermal growth receptor (EGFR) and (or) human EGFR2 (HER2), acquired or intrinsic resistance often confounds therapy success. Common mechanisms of therapy resistance involve activating receptor point mutations and (or) upregulation of signaling downstream of EGFR/HER2 to Akt and (or) mitogen activated protein kinase (MAPK) pathways. However, additional pathways of resistance may exist thus, confounding successful therapy.

Influence of Upper Airway Surgery on Voice and Speech Recognition.

Purpose: Upper airway surgery comprises a set of techniques that modify the anatomy of the vocal tract, including tonsillectomy and septoplasty. The objective of this work is to study the changes in acoustic parameters and the effects on the identification or verification of the speaker through the speech produced after the vocal tract surgeries, comparing them with a control group.

Methods: A prospective study was performed between January 2019 and June 2019 including.

COVID-19 pandemic lessons to facilitate future engagement in the global climate crisis.

The COVID-19 pandemic was declared a Public Health Emergency of International Concern (PHEIC) in January 2020. As of November 2020, over 54 million cases and over 1 million deaths have been reported globally. The sudden coronavirus global pandemic has also pointed to the importance of tackling the global climate crisis even more urgently.

A Case of Antibiotic-Induced Posterior Reversible Encephalopathy Syndrome.

To report a case of posterior reversible encephalopathy syndrome (PRES) in a 75 year-old patient who was taking concomitant ciprofloxacin and metronidazole. Case report A patient had been prescribed ciprofloxacin and metronidazole during a recent hospitalization and continued this regimen outpatient. Two weeks after discharge and 3 weeks after initiation of her regimen, she was brought to the emergency department after developing acute weakness and lightheadedness.