Palladium-catalyzed stereocontrolled ring-opening of 7-oxabenzonorbornadienes with organic carboxylic acids.

A palladium-catalyzed tandem reaction of 7-oxabenzonorbornadienes with organic carboxylic acids that provides -1,2-dihydro-l-naphthyl derivatives in moderate to good yields in a highly diastereoselective manner is described. A possible reaction mechanism involving acylation followed by insertion and diastereoselective ring-opening with 7-oxabenzonorbornadienes is proposed to account for the reaction.

Synthesis and DSSC application of BODIPY decorated triazole bridged and benzene nucleus cored conjugated dendrimers.

Conjugated dendrimers decorated with 5,5-difluoro-10-(4-(prop-2-ynyloxy)phenyl)-5-dipyrrolo[1,2-:1',2'-][1,3,2]diazaborinin-4-ium-5-uide, usually known as boron dipyrromethene (BODIPY), have been synthesized and their application as photosensitizer in dye sensitized solar cells (DSSCs) has been evaluated. Third generation triazole bridged BODIPY dendrimers show higher light energy harvesting efficiency of 2.5% better than the first and second generation dendrimers, when used as a dye material in solar cells.

Discovery of new potential triplet acting inhibitor for Alzheimer's disease via X-ray crystallography, molecular docking and molecular dynamics.

The most common brain disorder of late life is Alzheimer's disease (AD), which is highly complicating dementia. There are several drug targets which are reported to control the severe level of AD; notably, acetylcholinesterase, β-Secretase and glycogen synthase kinase enzymes are approached as a good drug targets for AD. Hence, the present study mainly focused to discover newly synthesized molecule (7-propyl-6H-pyrano[3,2-c:5,6-c']dichromene-6,8(7H)-dione) as a potential triplet acting drug for above said enzymes through the analysis of X-ray crystallography, molecular docking, molecular dynamics and quantum chemical calculation.