[Treatment of patients with 1B-stage cervical cancer].

An analysis of a more than 40-year experience of management of stage Ib, T1bN0M0 cervical cancer (611 cases) followed the development of combined treatment of the disease: Until 1970-ies, irradiation plus surgery was preferred. During the seventies no correlation between effectiveness and sequence of these component procedures was established. According to data on 33 surgical cases, extended extirpation of the uterus may be recommended in patients with stage Ib cervical cancer less than 5 mm deep and free from such adverse prognostic factors as concomitant pregnancy, poor cell differentiation and blood and lymph vascular microembolism by tumor.

[Clinico-morphologic parallels in synchronous cancer of the endometrium and ovaries].

A comparative study of 84 cases of endometrial and ovarian carcinoma showed clinical course of endometroid tumor to be more favorable than that of non-endometroid one (five-year survival--72.5 and 8.2%, respectively).

[Principles of specialized oncogynecologic services].

It is pointed out that distinctive features of malignant neoplasms of the female genital system determine peculiarity of organization of medical care for patients with cancer of uterus, ovary and external genital organs. Violation of the basic principle, i.e.

[Organ-preserving treatment in oncogynecology].

The paper discussed the results of organ-saving treatment carried out in 388 cases of cancer of the cervix uteri (Ca in situ), early endometrial carcinoma and stage IIa tumors of the ovary. The choice of the procedure should be made on reliable evidence on tumor extension and morphology. Favorable end results and preservation of reproductive function justify the use of said treatment and opens up new vistas in research.

[Clinical aspects of a synchronous cancerous lesion of the corpus uteri and the ovaries].

The results of a clinical study of 42 cases of synchronous endometrial and ovarian tumors are discussed. Clinical manifestations of synchronous cancer were found to be similar to those of endometrial carcinoma. Postmenopausal patients showed a favorable course of tumor process, thus suggesting its primary multiple origin, slightly more frequently than reproductive or climacteric females.

[The role of hormone therapy in the treatment of cancer of the endometrium].

Application of 17-oxyprogesterone-capronate as a component of complex treatment of 188 patients with stage I-III carcinoma of corpus uteri improved the long-term results at all stages of the process. Hormonotherapy should be recommended as a method of choice in the postoperative treatment of patients suffering from stage I-II endometrial carcinoma with superficial infiltration of the muscular layer or as an independent method of treatment in elderly patients in case of contraindications for surgery and radiation procedures. The method offers good advantages in young patients at the initial stages only.

[Clinico-morphological changes during treatment of endometrial cancer with progestins].

The results of the complex clinico-morphological study of the effect of 17-a-hydroxyprogesterone-caproate are reported in 71 patients aged from 37 to 75. Stage I was noted in 17 patients, stage II--in 51, stage III--in 3. A total dosage was 5,0; 10,0; 20,0 and 30,0 for the course of treatment.

[Combined and surgical treatment of cervical cancer].

The many-year experience with the treatment of cervical cancer in the gynecological clinic of the P. A. Herzen Research Institute of Oncology has indicated that a combined method in case of the appropriate indications provides for high and persistant late results.

[Cytodiagnosis of endometrial cancer].

Uterine aspiration specimens from 172 females were examined cytologically (cancer in 89, non-cancer process -- in 71, in 12 cases aspiration specimens were obtained in a reproductive period in proliferative and secretory phases of the menstrual cycle). It was shown that in a group of histologically verified observations in 45.8% a gynecologist failed to recognize the true endometrial affection.