Publications by authors named "Vegard A Forsaa"
Article Synopsis
- The study aims to analyze cytokine levels in the tear fluid of patients undergoing multiple intravitreal injections (IVI) of anti-VEGF for treating neovascular age-related macular degeneration (nAMD).
- Researchers measured the levels of six cytokines in the tears of treated and untreated eyes of patients, using a specific assay technique, at least four weeks after receiving an injection.
- Results showed that levels of two pro-inflammatory cytokines, IFN-γ and TNF, were lower in the injected eyes compared to the untreated eyes, supporting the notion that serial IVI treatment correlates with reduced inflammation and improved tear film health.
Reticular Pseudodrusen Voids after Rhegmatogenous Retinal Detachment.
Case Rep Ophthalmol
August 2023
We present a case of reticular pseudodrusen (RPD) regression on multimodal retinal imaging following a rhegmatogenous retinal detachment. Two mechanisms of action can be postulated. The subretinal deposits dissolve due to voluminous subretinal fluid during retinal separation from the retinal pigment epithelium and are in turn mechanically cleared during retinal re-attachment surgery.
View Article and Find Full Text PDFArticle Synopsis
- The study examines long-term visual function and outer retinal changes after fovea-off retinal detachment surgery.
- Data were collected from 38 patients at various intervals post-surgery, assessing visual acuity, metamorphopsia, aniseikonia, and outer retinal conditions.
- Results indicated significant visual improvement in the second year and a gradual normalization of outer retinal structures, though metamorphopsia and aniseikonia remained stable.
Purpose: To investigate the effects of serial intravitreal injections (IVIs) on the ocular surface and meibomian glands (MGs) in patients treated with anti-vascular endothelial growth factor (anti-VEGF) for neovascular age-related macular degeneration (nAMD).
Design: Retrospective, controlled, observational study.
Participants: Patients with nAMD receiving unilateral IVIs with anti-VEGF agents.
Purpose: To investigate whether air tamponade is noninferior to sulfur hexafluoride (SF) gas tamponade for small (≤ 250 μm) and medium-sized (> 250 μm and ≤ 400 μm) macular holes (MHs).
Design: Multicenter, randomized controlled, noninferiority trial.
Participants: Patients aged ≥ 18 years undergoing surgery for primary MHs of ≤ 400 μm in diameter.
Choosing Wisely: recommendations from the Norwegian Ophthalmological Society.
Acta Ophthalmol
September 2022
Background: To investigate the risk of primary macular hole (MH) in the fellow eye, and to evaluate baseline characteristics and optical coherence tomography (OCT) features that precede MH formation in the fellow eye.
Methods: A retrospective review of 229 patients treated for primary MH at Stavanger University Hospital, Norway, from January 2008 through December 2018. The patients were categorised into two groups according to subsequent development of MH in the fellow eye.
Purpose: To compare pathology detection using multicolor confocal scanning laser ophthalmoscopy with color fundus photography following macula-off rhegmatogenous retinal detachment.
Methods: Postsurgery multicolor confocal scanning laser ophthalmoscopy and color fundus photography images from 30 rhegmatogenous retinal detachment patients were examined by 10 masked graders. Imaging was performed with the Heidelberg Spectralis HRA and the digital retinal camera Basler acA2500-14gc GigE.
We present a case report of periocular . The key feature of distinguishing it from other human filarial parasites are cuticular bosses, which are presented in images from a light microscope and a scanning electron microscope. The cuticular bosses could be divided into three subtypes not previously described.
View Article and Find Full Text PDFPurpose: To review the incidence, aetiology and outcomes of endophthalmitis during a 20-year period in a Norwegian university hospital.
Methods: Single-centre retrospective review. Medical records of all patients admitted to Stavanger University Hospital with suspected endophthalmitis between January 1999 and December 2018 were reviewed.
Purpose: To explore the potentials of multicolor (MC) confocal scanning laser ophthalmoscopy (cSLO) to detect structural retinal pathology after macula-off rhegmatogenous retinal detachment (RRD) and to describe their appearances.
Methods: Thirty MC cSLO images of 30 eyes after RRD repair were prospectively studied for the presence of RRD-related pathology. All MC cSLO findings were verified using swept source optical coherence tomography.
Purpose: To evaluate the postoperative closure rate of full-thickness macular holes (MHs) after nonsupine positioning, which means that the patients avoid upward gaze and a supine sleeping position, and to investigate the correlation between postoperative positioning compliance and closure rate.
Design: Prospective, multicenter study (ClinicalTrials.gov identifier, NCT02295943).
Purpose: To investigate the incidence of full-thickness macular holes (FTMHs) and their morphological features according to the International Vitreomacular Traction Study (IVTS) classification.
Methods: The clinical records of all new patients with FTMH, referred between 2008 and 2014, were reviewed for demographics, cause of the FTMH, age at diagnosis, symptom duration, laterality, visual acuity (VA), axial length and lens status. A detailed analysis of the patients' spectral domain optical coherence tomography (SD-OCT) images was performed, and the primary FTMHs were classified in clinical stages according to the IVTS classification.
Purpose: To investigate the closure rate of primary full-thickness macular hole, following intraocular air tamponade combined with a nonsupine positioning regimen.
Methods: A prospective study of patients with full-thickness macular hole, who underwent pars plana vitrectomy with internal limiting membrane peeling and intraocular air tamponade followed by 3 days of nonsupine positioning. Outcome measures were primary full-thickness macular hole closure and improvement in best-corrected visual acuity after 6 months.
Purpose: To objectively evaluate patients' compliance with a nonsupine positioning (NSP) regimen after macular hole surgery and to investigate whether supine positioning time during the first postoperative nights is reduced when a tennis ball is mounted onto the back of the nightshirt.
Methods: A "position monitoring device" capable of recording the time the head is kept in a supine position was attached to the patient's forehead. In a randomized, controlled, crossover study, the accumulated time each patient spent in a supine position was recorded during two consecutive postoperative nights, both when the "tennis ball technique" (TBT) was used and when it was not, respectively.
Purpose: The purpose of this study was to compare the efficacy of short-term non-supine positioning (NSP) and strict face-down positioning (FDP) in the repair of macular hole (MH).
Methods: We retrospectively reviewed all MH repairs over a 27-month period (2008-2010). Inclusion criteria were idiopathic full thickness stage 2-4 MH treated by a single surgeon with 23-gauge pars plana vitrectomy, internal limiting membrane peeling and gas tamponade, followed by postoperative short-term NSP (for 5 days) or strict FDP (for 3-4 days).