Publications by authors named "Veerle Willaeys"
SETD1A variant-associated psychosis: A systematic review of the clinical literature and description of two new cases.
Prog Neuropsychopharmacol Biol Psychiatry
February 2024
Article Synopsis
- SETD1A is a gene that encodes a histone methyltransferase linked to cell cycle regulation and has been associated with neurodevelopmental disorders like intellectual disability and schizophrenia.
- This study systematically reviews existing literature and presents new case reports to better understand the psychiatric symptoms and neurodevelopmental features of individuals with SETD1A variants related to schizophrenia.
- Findings suggest that while people with SETD1A-linked schizophrenia share some traits, there’s significant variability in their symptoms, and recognizing these variants could be important for future personalized treatment options in mental health care.
Chromosome 1p32-p31 deletion syndrome, which is characterized by a variety of neurodevelopmental abnormalities, is thought to occur as a result of nuclear factor 1A () haploinsufficiency. We present a case of a right-handed 40-year-old female with a 1p31.3 deletion, who exhibited numerous common features of this syndrome, in addition to treatment resistant schizoaffective disorder and possible temporal lobe epilepsy, making her presentation unique.
View Article and Find Full Text PDF