Publications by authors named "Veerle Desloovere"
Article Synopsis
- Cerebrovascular autoregulation (CA) can be disrupted after acute brain injuries, and different levels of carbon dioxide (PaCO₂) influence this regulation, though the specifics are not well understood.
- This study aimed to examine how changes in PaCO₂ affect pial vasodynamics using a porcine model, preparing for further research on cerebral blood flow (CBF) under varying PaCO₂ levels.
- Results showed that modifying respiratory rates to adjust PaCO₂ was effective, and while there were changes in pial arteriolar diameter with PaCO₂ variations, significant vasodilation only occurred in a hypercapnic environment, indicating a non-linear relationship.
Background: The objective of this study was to describe changes in cerebral tissue oxygen saturation (SctO2) due to changes in body position in healthy volunteers and in patients undergoing surgery under general anesthesia in the beach chair position (BCP) and lateral decubitus position (LDP).
Methods: In this prospective observational study, SctO2 was measured in 85 awake volunteers serially positioned every 15 min, beginning with the supine position (SP) and followed by the beach chair, supine, and lateral decubitus positions. Cerebral tissue oxygen saturation was also measured supine and in either the BCP or the LDP in 195 patients (according to surgical preference) undergoing elective arthroscopic shoulder surgery.