Microsporidial Stromal Keratitis: Clinical Features, Unique Diagnostic Criteria, and Treatment Outcomes in a Large Case Series.

Purpose: To describe the history, clinical features, and outcomes of a large case series of microsporidial stromal keratitis with emphasis on probable predictors of the etiology in this rare and unspecified form of keratitis.

Methods: Retrospective analysis of cases seen between January, 2002, and December, 2013, diagnosed at LV Prasad Eye Institute as having microsporidial stromal keratitis based on clinical, microbiology, and histopathology examination. Outcomes of medical and surgical management with visual recovery were documented.

Bilateral big-bubble deep anterior lamellar keratoplasty for vascularised corneal opacity in a patient with xeroderma pigmentosum.

A 16-year-old male patient diagnosed with xeroderma pigmentosum developed bilateral vascularised corneal opacities after treatment for ocular surface squamous neoplasia. The patient underwent an uneventful big-bubble deep anterior lamellar keratoplasty in both eyes. The grafts remained clear and the corrected distance visual acuity was 20/30 in both the eyes at the final follow-up visit.