Previous studies, using the Continuous Flash Suppression (CFS) paradigm, observed that (Western) university students are better able to detect otherwise invisible pictures of objects when they are presented with the corresponding spoken word shortly before the picture appears. Here we attempted to replicate this effect with non-Western university students in Goa (India). A second aim was to explore the performance of (non-Western) meditators practicing Sudarshan Kriya Yoga in Goa in the same task.
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March 2024
Introduction: Epilepsy is a chronic neurological disorder characterized by abnormal electrical activity in the brain, often leading to recurrent seizures. With 50 million people worldwide affected by epilepsy, there is a pressing need for efficient and accurate methods to detect and diagnose seizures. Electroencephalogram (EEG) signals have emerged as a valuable tool in detecting epilepsy and other neurological disorders.
View Article and Find Full Text PDFBackground: The study of brain networks, particularly the spread of disease, is made easier thanks to the network theory. The aberrant accumulation of beta-amyloid plaques and tau protein tangles in Alzheimer's disease causes disruption in brain networks. The evaluation scores, such as the mini-mental state examination (MMSE) and neuropsychiatric inventory questionnaire, which provide a clinical diagnosis, are affected by this build-up.
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December 2022
Emotion classification using electroencephalography (EEG) data and machine learning techniques have been on the rise in the recent past. However, past studies use data from medical-grade EEG setups with long set-up times and environment constraints. This paper focuses on classifying emotions on the valence-arousal plane using various feature extraction, feature selection, and machine learning techniques.
View Article and Find Full Text PDFReinforcement learning methods have recently been very successful at performing complex sequential tasks like playing Atari games, Go and Poker. These algorithms have outperformed humans in several tasks by learning from scratch, using only scalar rewards obtained through interaction with their environment. While there certainly has been considerable independent innovation to produce such results, many core ideas in reinforcement learning are inspired by phenomena in animal learning, psychology and neuroscience.
View Article and Find Full Text PDFFront Aging Neurosci
February 2021
Current methods for early diagnosis of Alzheimer's Dementia include structured questionnaires, structured interviews, and various cognitive tests. Language difficulties are a major problem in dementia as linguistic skills break down. Current methods do not provide robust tools to capture the true nature of language deficits in spontaneous speech.
View Article and Find Full Text PDFAnnu Int Conf IEEE Eng Med Biol Soc
July 2017
The ability to interpret unspoken or imagined speech through electroencephalography (EEG) is of therapeutic interest for people suffering from speech disorders and `lockedin' syndrome. It is also useful for brain-computer interface (BCI) techniques not involving articulatory actions. Previous work has involved using particular words in one chosen language and training classifiers to distinguish between them.
View Article and Find Full Text PDFA fundamental goal in cellular signaling is to understand allosteric communication, the process by which signals originating at one site in a protein propagate reliably to affect distant functional sites. The general principles of protein structure that underlie this process remain unknown. Statistical coupling analysis (SCA) is a statistical technique that uses evolutionary data of a protein family to measure correlation between distant functional sites and suggests allosteric communication.
View Article and Find Full Text PDFFatty acid biosynthesis of Mycobacterium tuberculosis was analyzed using graph theory and influential (impacting) proteins were identified. The graphs (digraphs) representing this biological network provide information concerning the connectivity of each protein or metabolite in a given pathway, providing an insight into the importance of various components in the pathway, and this can be quantitatively analyzed. Using a graph theoretic algorithm, the most influential set of proteins (sets of {1, 2, 3}, etc.
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