Publications by authors named "Vediyera Chandroth Santhosh"
Drug-induced gingival overgrowth is a frequently observed adverse effect of antihypertensive drug calcium channel blockers (CCBs). Gingival enlargements are more common with the dihydropyridine class of CCBs. The fourth-generation dihydropyridine CCB Cilnidipine was introduced in 1995 and is used as an antihypertensive agent for patients in the Indian subcontinent.
View Article and Find Full Text PDFThe myelodysplastic syndrome (MDS) is characterized by peripheral blood cytopenias and increased risk of transformation to acute myeloid leukemia. This syndrome affects blood cell production and behavior. MDS is difficult to diagnose because of the absence of symptoms in the early stage of the disease.
View Article and Find Full Text PDFArticle Synopsis
- The study investigated gingival overgrowth (GO) as a side effect of calcium channel blockers, focusing on nifedipine, diltiazem, and amlodipine.
- It was a cross-sectional study of 133 patients that assessed GO prevalence and evaluated oral hygiene through various indices.
- Results indicated that nifedipine users had the highest GO occurrence at 75%, highlighting poor oral hygiene and gingival inflammation as significant risk factors.