Publications by authors named "Vaughan M"

Aim: The aim of this literature review was to determine if a consensus could be reached on whether amblyopia treatment causes distress to patients and/or their guardians, and if so, establish the impact of this reported psychological distress upon paediatric patients and/or their parents/guardians.

Methods: A systematic review of the literature was conducted of all publications written in English. Search terms included both MeSH terms and alternatives related to amblyopia and psychological distress.

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  • A study was conducted from September 2022 to April 2023 to evaluate how COVID-19 vaccines affect the risk of infection in children under 5 years old.
  • The results showed no significant difference in infection risk between vaccinated and unvaccinated children.
  • Although the vaccines are effective in preventing severe illness, they may not prevent the actual infection of the virus in young kids.
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Purpose: Although it is well known that photoreceptor damage and color vision loss occur in patients with diabetic retinopathy (DR), the relationship between structural and functional changes in diabetes mellitus (DM) remains unclear. Using highly sensitive measures of photoreceptor structure and function, we aim to determine whether early loss of color sensitivity in DM is also accompanied by decreased cone density.

Methods: Monocular data from 26 patients with DM and 25 healthy controls were examined to assess cone photoreceptor metrics, using confocal adaptive optics scanning light ophthalmoscopy, and red/green (RG) and yellow/blue (YB) color vision thresholds, using the Colour Assessment and Diagnosis test.

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  • The study investigates the optical conductivity and magnetotransport properties of top-gated devices made from the topological insulator BiSe, focusing on how different carrier types within the material interact.
  • Findings reveal that the topologically protected surfaces are somewhat shielded from gate control due to trivial band-bending states but still show significant mobility changes based on external gate bias.
  • The research highlights that the optical conductivity is largely influenced by the topological surface states and is particularly affected by scattering from trivial states, suggesting potential uses in future plasmonic device designs.
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Fusarium ear rot (FER) and Gibberella ear rot (GER) caused by Fusarium species are major diseases affecting maize production in Ethiopia. In addition to reducing quality and yield, these fungi can produce mycotoxins that contaminate maize kernels and, thereby, pose health hazards to humans and livestock. A survey was conducted in 10 administrative zones of Ethiopia within the major maize-growing regions of the country to identify the species of Fusarium associated with ear rot.

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Femoral hernias are at a high risk of strangulation due to their narrow necks. They are an exceptionally rare occurrence in males. In many cases, differentiation between a femoral and inguinal hernia is difficult.

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  • * The Health Equity Indicators for Cardiovascular Disease Toolkit (HEI for CVD Toolkit) provides essential resources, including metrics and guidance, to help healthcare professionals analyze and address CVD inequities.
  • * Developed through literature reviews and expert engagements, the toolkit helps users understand health inequities, measure progress, and evaluate interventions in their communities.
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  • The study focuses on the pathogen responsible for Fusarium head blight (FHB) in grains like wheat and barley, emphasizing its role in yield loss and mycotoxin contamination.
  • Researchers identified three North American populations with distinct trichothecene chemotypes and found that the NA3 population had unique characteristics, including higher toxin production in wheat despite less spread.
  • In barley, the NA1 population caused more severe symptoms, but the NA3 population still outperformed it in terms of toxin production, highlighting the potential threat of the emerging NA3 population to crops.
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Unlabelled: Hybrid immunity, as a result of infection and vaccination to SARS-CoV-2, has been well studied in adults but limited evidence is available in children. We evaluated the antibody responses to primary SARS-CoV-2 infection among vaccinated and unvaccinated children aged ≥ 5 years.

Methods: A longitudinal cohort study of children aged ≥ 5 was conducted during August 2021-August 2022, at sites in Arizona, Texas, Utah, and Florida.

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In 2021, the Centers for Disease Control and Prevention's (CDC) National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP) funded community health workers (CHWs) for COVID Response and Resilient Communities (CCR). CCR is a 3-year, $350 million initiative to implement CHW strategies aimed at reducing COVID-19 impacts, building resilience, and improving health equity by addressing health-related social needs. This paper describes the CCR initiative and experiences to date, underscoring CHWs' critical role in CDC's pandemic response.

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Diabetes remains a major, global clinical and public health threat with consistent rises in prevalence around the world over the past four decades. Two-thirds of the projected increases in global diabetes prevalence to 2045 are expected to come from low- and middle-income countries, including those in sub-Saharan Africa. Ghana is typical of this trend.

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Animal agriculture is under pressure to increase efficiency, sustainability, and innovation to meet the demands of a rising global population while decreasing adverse environmental effects. Feed cost and availability are 2 of the biggest hurdles to sustainable production. Current diets depend on sources of grain and animal byproduct protein for essential amino acids which have limited sustainability.

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Context: Contributing to the evidence base, by disseminating findings through written products such as journal articles, is a core competency for public health practitioners. Disseminating practice-based evidence that supports improving cardiovascular health is necessary for filling literature gaps, generating health policies and laws, and translating evidence-based strategies into practice. However, a gap exists in the dissemination of practice-based evidence in public health.

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  • Missions into Deep Space this decade are concerning due to potential health risks from microgravity and galactic cosmic radiation, especially for kidneys.
  • Researchers used various biological and clinical analyses on samples from spaceflight-exposed mice, humans, and simulated environments.
  • Key findings reveal that spaceflight causes kidney-related issues like increased risk of kidney stones, changes in nephron structure, and damage from radiation exposure.
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The fungal infestation of crops can cause major economic losses. Toxins produced by the causative fungi (mycotoxins) represent a potential safety hazard to people and livestock consuming them. One such mycotoxin is deoxynivalenol (DON, also known as vomitoxin), a trichothecene associated with Fusarium Head Blight of wheat.

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Purpose: To compare the ocular effects of exposure to a low-humidity environment with and without contact lens (CL) wear using various non-invasive tests.

Methods: Fourteen habitual soft CL wearers were exposed to controlled low humidity (5% relative humidity [RH]) in an environmental chamber for 90 min on two separate occasions. First, when wearing their habitual spectacles and then, on a separate visit, when wearing silicone hydrogel CLs that were fitted specifically for this purpose.

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Introduction: Artificial Intelligence (AI) chatbots are able to explain complex concepts using plain language. The aim of this study was to assess the accuracy of three AI chatbots answering common questions related to contact lens (CL) wear.

Methods: Three open access AI chatbots were compared: Perplexity, Open Assistant and ChatGPT 3.

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Mental health advocacy and activism have been highlighted as important in the effort towards creating environments for better mental health. However, relevant research in low- and middle-income country settings remains limited and lacks critical exploration. We seek to contribute to filling this gap by exploring driving factors behind mental health advocacy and activism efforts in low- and middle-income country settings.

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Psycholeptic and specifically antipsychotic prescribing is increasing worldwide each year. This study aims to investigate the prevalence and cost of antipsychotic prescribing, within the wider frame of psycholeptic prescribing, in the Irish context. Quantitative analysis of a dataset from the Primary Care Reimbursement Service relating to cost and prescribing frequency of ATC Class N05 psycholeptic drugs from January 2020-August 2022 inclusive was conducted using Microsoft Excel for Microsoft 365 MSO (Version 2311) and STATA 18.

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  • * Limited data exists regarding the effectiveness of these vaccines, prompting the need for this research to understand their impact on this age group and inform vaccination strategies.
  • * The analysis involved testing nasal swabs for the virus and comparing infection rates between vaccinated participants and those who were unvaccinated or had received only monovalent vaccine doses, while controlling for various demographic and health factors.
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Objectives: Pediatric COVID-19 vaccine hesitancy and uptake is not well understood. Among parents of a prospective cohort of children aged 6 months-17 years, we assessed COVID-19 vaccine knowledge, attitudes, and practices (KAP), and uptake over 15 months.

Methods: The PROTECT study collected sociodemographic characteristics of children at enrollment and COVID-19 vaccination data and parental KAPs quarterly.

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Post-infection inflammatory syndromes have been increasingly recognized as a cause of host damage in a variety of infectious diseases including tuberculosis, bacterial meningitis, and COVID-19. Recently, a post-infectious inflammatory response syndrome (PIIRS) was described in non-HIV-infected cryptococcal fungal meningoencephalitis (CM) as a major cause of mortality. Inflammatory syndromes are particularly severe in neurological infections due to the skull's rigid structure which limits unchecked tissue expansion from inflammatory-induced edema.

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Purpose: Detailed reporting of individually tailored exercise prescriptions (ExR x ) used in clinical trials is essential to describe feasibility, tolerability, and efficacy of the intervention and to inform translation to clinical care. This article outlines the methodology used to develop a resistance training (RT) ExR x for people with colon cancer receiving chemotherapy and reports adherence to the randomized controlled trial testing the impact of RT on relative dose intensity of chemotherapy and patient-reported toxicities.

Methods: Participants randomized to the exercise arm ( n = 90) were included.

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In the USA, structural racism contributes to higher rates of cardiovascular disease (CVD) including hypertension, heart disease, and stroke among African American persons. Evidence-based interventions (EBIs), which include programs, policies, and practices, can help mitigate health inequities, but have historically been underutilized or misapplied among communities experiencing discrimination and exclusion. This commentary on the special issue of Prevention Science, "Advancing the Adaptability of Chronic Disease Prevention and Management Through Implementation Science," describes the Centers for Disease Control and Prevention, Division for Heart Disease and Stroke Prevention's (DHDSP's) efforts to support implementation practice and highlights several studies in the issue that align with DHDSP's methods and mission.

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